Acylglycerol Kinase, Mitochondrial (AGK) Antibody

Este producto es parte de AGK - Acylglycerol Kinase:Acylglycerol kinase
Acylglycerol Kinase, Mitochondrial (AGK) Antibody

Pida mas información

935106861

info@markelab.com

Precio

195€ (20 µl)

Antibody anti-AGK

proveedor

Abbexa

reference

abx135896

Tested Applications

ELISA, WB

reactivity

Human, Rat

status

RUO

clonality

Polyclonal

Descripción

AGK Antibody is a Rabbit Polyclonal against AGK.


Background

Acylglycerol kinase (AGK) is a mitochondrial enzyme that catalyzes the phosphorylation of monoacylglycerol and diacylglycerol to produce lysophosphatidic acid (LPA) and phosphatidic acid (PA), which are critical intermediates in lipid metabolism, membrane biosynthesis, and intracellular signaling pathways. AGK also plays an essential role in the assembly and stability of mitochondrial respiratory chain supercomplexes, ensuring efficient oxidative phosphorylation and ATP production. This dual function underscores its importance in both energy metabolism and lipid signaling. Mutations in the AGK gene are associated with Sengers syndrome, a rare mitochondrial disorder characterized by cardiomyopathy, cataracts, skeletal myopathy, and lactic acidosis. Dysregulation of AGK has also been linked to cancer progression, where it enhances tumor growth by modulating lipid-derived signaling molecules and energy homeostasis. AGK is gaining attention as a therapeutic target in cancer and mitochondrial dysfunction, with research exploring its potential in restoring metabolic balance and energy efficiency.

Características del producto

category

Primary Antibodies


clonality

Polyclonal


reactivity

Human, Rat


immunogen target

Acylglycerol Kinase, Mitochondrial (AGK)


host

Rabbit


isotype

IgG


conjugation

Unconjugated


form

Liquid


tested applications

ELISA, WB


purification

Purified by affinity chromatography.


recommended dilution

ELISA: 1 µg/ml, WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.


buffer

PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.


size 1

20 µl


size 2

100 µl


size 3

2 × 100 µl


storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.


or code

AGK


dry ice

No


availability

Shipped within 5-10 working days.


alias

CATC5,CTRCT38,MTDPS10,MULK


NCBI accession

NP_060708.1


note

Concentration: > 0.2 mg/ml -


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