Acylglycerol Kinase, Mitochondrial (AGK) Antibody
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935106861
info@markelab.com
Precio
195€ (20 µl)
Antibody anti-AGK
proveedor
Abbexareference
abx135896Tested Applications
ELISA, WBreactivity
Human, Ratstatus
RUOclonality
PolyclonalDescripción
AGK Antibody is a Rabbit Polyclonal against AGK.
Background
Acylglycerol kinase (AGK) is a mitochondrial enzyme that catalyzes the phosphorylation of monoacylglycerol and diacylglycerol to produce lysophosphatidic acid (LPA) and phosphatidic acid (PA), which are critical intermediates in lipid metabolism, membrane biosynthesis, and intracellular signaling pathways. AGK also plays an essential role in the assembly and stability of mitochondrial respiratory chain supercomplexes, ensuring efficient oxidative phosphorylation and ATP production. This dual function underscores its importance in both energy metabolism and lipid signaling. Mutations in the AGK gene are associated with Sengers syndrome, a rare mitochondrial disorder characterized by cardiomyopathy, cataracts, skeletal myopathy, and lactic acidosis. Dysregulation of AGK has also been linked to cancer progression, where it enhances tumor growth by modulating lipid-derived signaling molecules and energy homeostasis. AGK is gaining attention as a therapeutic target in cancer and mitochondrial dysfunction, with research exploring its potential in restoring metabolic balance and energy efficiency.
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Human, Rat
immunogen target
Acylglycerol Kinase, Mitochondrial (AGK)
host
Rabbit
isotype
IgG
conjugation
Unconjugated
form
Liquid
tested applications
ELISA, WB
purification
Purified by affinity chromatography.
recommended dilution
ELISA: 1 µg/ml, WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
buffer
PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
size 1
20 µl
size 2
100 µl
size 3
2 × 100 µl
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
or code
AGK
dry ice
No
availability
Shipped within 5-10 working days.
alias
CATC5,CTRCT38,MTDPS10,MULK
uniprot id
NCBI accession
NP_060708.1
note
Concentration: > 0.2 mg/ml -
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