Human Acylglycerol Kinase (AGK) CLIA Kit
845€ (96 tests)
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name
Human Acylglycerol Kinase (AGK) CLIA Kit
category
CLIA Kits
provider
Abbexa
reference
abx495134
tested applications
CLIA
Description
Human AGK Chemiluminescent Immunoassay (CLIA) Kit is a Sandwich Chemiluminescent Immunoassay (CLIA) Kit for use with Tissue homogenates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | CLIA Kits |
| Immunogen Target | Acylglycerol Kinase (AGK) |
| Reactivity | Human |
| Detection Method | Chemiluminescent |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Sensitivity | < 0.081 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | CLIA |
| Sample Type | Tissue homogenates and other biological fluids. |
| Availability | Shipped within 5-20 working days. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| Alias | CATC5,CTRCT38,MTDPS10,MULK |
| Background | CLIA Kits AGK |
| Status | RUO |
| Note | The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
Acylglycerol kinase (AGK) is a mitochondrial enzyme that catalyzes the phosphorylation of monoacylglycerol and diacylglycerol to produce lysophosphatidic acid (LPA) and phosphatidic acid (PA), which are critical intermediates in lipid metabolism, membrane biosynthesis, and intracellular signaling pathways. AGK also plays an essential role in the assembly and stability of mitochondrial respiratory chain supercomplexes, ensuring efficient oxidative phosphorylation and ATP production. This dual function underscores its importance in both energy metabolism and lipid signaling. Mutations in the AGK gene are associated with Sengers syndrome, a rare mitochondrial disorder characterized by cardiomyopathy, cataracts, skeletal myopathy, and lactic acidosis. Dysregulation of AGK has also been linked to cancer progression, where it enhances tumor growth by modulating lipid-derived signaling molecules and energy homeostasis. AGK is gaining attention as a therapeutic target in cancer and mitochondrial dysfunction, with research exploring its potential in restoring metabolic balance and energy efficiency.
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