Human Acyl-coenzyme A thioesterase 1 (ACOT1) ELISA Kit
715€ (96 tests)
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935106861
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name
Human Acyl-coenzyme A thioesterase 1 (ACOT1) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx500820
tested applications
ELISA
Description
Human Acyl-coenzyme A thioesterase 1 (ACOT1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Acyl-coenzyme A thioesterase 1 (ACOT1) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Acyl-coenzyme A thioesterase 1 (ACOT1) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q86TX2 |
| OMIM | 614313 |
| Alias | ACH2,CTE-1,LACH2 |
| Background | Elisa kits for ACOT1 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
ACOT1 is a cytosolic enzyme that hydrolyzes acyl-CoA molecules into free fatty acids and CoA, thereby playing a critical role in lipid metabolism and energy homeostasis. It is expressed predominantly in tissues such as the liver, skeletal muscle, and adipose tissue, where it regulates intracellular fatty acid availability for β-oxidation or lipid signaling. By modulating acyl-CoA levels, ACOT1 influences processes such as energy production, lipid storage, and peroxisomal metabolism. It is also implicated in the regulation of metabolic flexibility during fasting and fed states, as it ensures a balance between fatty acid oxidation and esterification. Dysregulation of ACOT1 activity has been linked to metabolic diseases, including obesity, diabetes, and non-alcoholic fatty liver disease, where altered lipid metabolism contributes to disease progression. Its enzymatic activity and specificity for medium- and long-chain acyl-CoAs make ACOT1 a critical regulator of lipid homeostasis and a potential therapeutic target in metabolic disorders.
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