Acyl-Coenzyme A Thioesterase 1 (ACOT1) Antibody
357.5€ (100 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Acyl-Coenzyme A Thioesterase 1 (ACOT1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx038129
tested applications
ELISA, WB, IHC
Description
Rabbit Polyclonal against the ACOT1 protein.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Acyl-Coenzyme A Thioesterase 1 (ACOT1) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000, IHC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by Protein A/G column chromatography. |
| Size 1 | 100 µg |
| Size 2 | 1 mg |
| Form | Lyophilized |
| Tested Applications | ELISA, WB, IHC |
| Buffer | Prior to lyophilization: 0.02% NaN3. |
| Availability | Shipped within 7-15 working days. |
| Storage | Store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | ACH2,CTE-1,LACH2 |
| Background | Antibody anti-ACOT1 |
| Status | RUO |
| Note | Concentration: Lyophilized form: Not applicable. After reconstitution: 1 mg/ml. - |
Descripción
ACOT1 is a cytosolic enzyme that hydrolyzes acyl-CoA molecules into free fatty acids and CoA, thereby playing a critical role in lipid metabolism and energy homeostasis. It is expressed predominantly in tissues such as the liver, skeletal muscle, and adipose tissue, where it regulates intracellular fatty acid availability for β-oxidation or lipid signaling. By modulating acyl-CoA levels, ACOT1 influences processes such as energy production, lipid storage, and peroxisomal metabolism. It is also implicated in the regulation of metabolic flexibility during fasting and fed states, as it ensures a balance between fatty acid oxidation and esterification. Dysregulation of ACOT1 activity has been linked to metabolic diseases, including obesity, diabetes, and non-alcoholic fatty liver disease, where altered lipid metabolism contributes to disease progression. Its enzymatic activity and specificity for medium- and long-chain acyl-CoAs make ACOT1 a critical regulator of lipid homeostasis and a potential therapeutic target in metabolic disorders.
Related Products
Acyl-Coenzyme A Thioesterase 1 (ACOT1) Antibody
Rabbit Polyclonal against the ACOT1 protein.
Ver ProductoAcyl-CoA Thioesterase 1 (ACOT1) Antibody
ACOT1 Antibody is a Rabbit Polyclonal against ACOT1.
Ver ProductoAcyl-CoA Thioesterase 1 (ACOT1) Antibody
ACOT1 Antibody is a Rabbit Polyclonal against ACOT1.
Ver Producto