Human Acyl-CoA Thioesterase 6 (ACOT6) ELISA Kit
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935106861
info@markelab.com
Precio
687.5€ (96 tests)
Elisa Kits ACOT6
proveedor
Abbexareference
abx385583Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human Acyl-CoA Thioesterase 6 (ACOT6) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Acyl Coenzyme A Thioesterase 6 (ACOT6) concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
ACOT6 is a peroxisomal enzyme that hydrolyzes short- and medium-chain acyl-CoA molecules into free fatty acids and CoA, playing a critical role in peroxisomal lipid metabolism and the detoxification of acyl-CoA intermediates. It is expressed in metabolically active tissues such as the liver and kidney, where it participates in the breakdown of branched-chain fatty acids and bile acid intermediates. By regulating acyl-CoA and CoA levels, ACOT6 prevents the accumulation of potentially toxic lipid intermediates while supporting peroxisomal β-oxidation and cellular lipid homeostasis. Dysregulation of ACOT6 has been associated with metabolic disorders, including fatty acid oxidation deficiencies and lipid storage diseases, where impaired lipid processing leads to cellular dysfunction. Its role in maintaining peroxisomal balance underscores its importance in systemic metabolic health and adaptability during periods of metabolic stress.
Características del producto
category
ELISA Kits
immunogen target
Acyl-CoA Thioesterase 6 (ACOT6)
reactivity
Human
test range
0.313 ng/ml - 20 ng/ml
sensitivity
< 0.19 ng/ml
assay type
Sandwich
assay data
Quantitative
detection method
Colorimetric
sample type
Tissue homogenates,Cell lysates,Other biological fluids
size 1
96 tests
size 2
5 × 96 tests
size 3
10 × 96 tests
alias
C14orf42,c14_5530
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
ACOT6
dry ice
No
uniprot id
note
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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