Human Acyl-CoA Synthetase Short-Chain Family Member 3 (ACSS3) ELISA Kit

Este producto es parte de ACSS - Acyl-CoA Synthetase Short-Chain Family Member
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715€ (96 tests)

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935106861
info@markelab.com
name
Human Acyl-CoA Synthetase Short-Chain Family Member 3 (ACSS3) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx385601
tested applications
ELISA

Description

Human Acyl-CoA Synthetase Short-Chain Family Member 3 (ACSS3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Acyl Coenzyme A Synthetase Short Chain Family, Member 3 (ACSS3) concentrations in tissue homogenates, cell lysates and other biological fluids.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
ELISA Kits
Immunogen Target
Acyl-CoA Synthetase Short-Chain Family Member 3 (ACSS3)
Reactivity
Human
Detection Method
Colorimetric
Assay Data
Quantitative
Assay Type
Sandwich
Test Range
0.313 ng/ml - 20 ng/ml
Sensitivity
< 0.19 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Size 2
5 × 96 tests
Size 3
10 × 96 tests
Form
Lyophilized
Tested Applications
ELISA
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 5-12 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
Q9H6R3
Gene ID
79611
OMIM
614356
Alias
ACSS3
Background
Elisa kits for ACSS3
Status
RUO
Note
Validity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request.
This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

ACSS3 is a mitochondrial enzyme that activates short-chain fatty acids, such as propionate and acetate, converting them into their CoA derivatives for use in metabolic pathways like the TCA cycle and gluconeogenesis. It is predominantly expressed in the liver and kidneys, where it supports energy production and metabolic flexibility, particularly during fasting or other energy-demanding states. ACSS3 is involved in the metabolism of short-chain fatty acids derived from the gut microbiota, linking microbial activity to host energy homeostasis. Its activity ensures the efficient utilization of short-chain fatty acids, preventing their accumulation and associated metabolic imbalances. Dysregulation of ACSS3 has been associated with metabolic disorders, including propionic acidemia and other fatty acid metabolism-related conditions, emphasizing its importance in maintaining energy balance and metabolic health.

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