Acyl-CoA Synthetase Short-Chain Family Member 3 (ACSS3) Antibody
292.5€ (80 µl)
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935106861
info@markelab.com
name
Acyl-CoA Synthetase Short-Chain Family Member 3 (ACSS3) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx034007
tested applications
ELISA, WB
Description
ACSS3 activates acetate so that it can be used for lipid synthesis or for energy generation.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Acyl-CoA Synthetase Short-Chain Family Member 3 (ACSS3) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9H6R3 |
| Alias | ACSS3 |
| Background | Antibody anti-ACSS3 |
| Status | RUO |
Descripción
ACSS3 is a mitochondrial enzyme that activates short-chain fatty acids, such as propionate and acetate, converting them into their CoA derivatives for use in metabolic pathways like the TCA cycle and gluconeogenesis. It is predominantly expressed in the liver and kidneys, where it supports energy production and metabolic flexibility, particularly during fasting or other energy-demanding states. ACSS3 is involved in the metabolism of short-chain fatty acids derived from the gut microbiota, linking microbial activity to host energy homeostasis. Its activity ensures the efficient utilization of short-chain fatty acids, preventing their accumulation and associated metabolic imbalances. Dysregulation of ACSS3 has been associated with metabolic disorders, including propionic acidemia and other fatty acid metabolism-related conditions, emphasizing its importance in maintaining energy balance and metabolic health.
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