Human Activin A Receptor Type I (ACVR1) Protein

Este producto es parte de ACVR - Activin A Receptor Type
Human Activin A Receptor Type I (ACVR1) Protein

Pida mas información

935106861

info@markelab.com

Precio

212.5€ (10 µg)

Protein ACVR1

proveedor

Abbexa

reference

abx065132

Tested Applications

WB, SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Recombinant ACVR1 (ACVR1) is a recombinant Human protein produced in E. coli using Prokaryotic expression.


Background

ACVR1, also called ALK2 (Activin Receptor-Like Kinase 2), is a transmembrane serine/threonine kinase receptor. It binds ligands like BMPs (Bone Morphogenetic Proteins), initiating intracellular SMAD signaling. This receptor plays a crucial role in bone development, embryogenesis, and organogenesis. Mutations in ACVR1 are linked to fibrodysplasia ossificans progressiva (FOP), a rare disorder where soft tissues progressively ossify. Structurally, it comprises an extracellular ligand-binding domain, a single transmembrane helix, and an intracellular kinase domain.

Características del producto

category

Proteins and Peptides


origin

Human


host

E. coli


immunogen target

Activin A Receptor Type I (ACVR1)


host

E. coli


conjugation

Unconjugated


form

Lyophilized


tested applications

WB, SDS-PAGE


size 1

10 µg


size 2

50 µg


size 3

100 µg


size 4

200 µg


size 5

1 mg


expression

Recombinant


purity

> 95%


buffer

Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.


storage

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.


or code

ACVR1


dry ice

No


availability

Shipped within 5-12 working days.


alias

ACVRLK2


note

This product is for research use only. <p></p> Not for human consumption, cosmetic, therapeutic or diagnostic use.


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