Human Activin A Receptor Type I (ACVR1) Protein
![Human Activin A Receptor Type I (ACVR1) Protein](/_next/image?url=https%3A%2F%2Fwww.abbexa.com%2Fimage%2Fcache%2Fdata%2Fproducts%2F21%2Fabx065132_Human_ACVR1_Protein_SDSPAGE-180x180.jpg&w=3840&q=75)
Pida mas información
935106861
info@markelab.com
Precio
212.5€ (10 µg)
Protein ACVR1
proveedor
Abbexareference
abx065132Tested Applications
WB, SDS-PAGEreactivity
status
RUOclonality
Descripción
Recombinant ACVR1 (ACVR1) is a recombinant Human protein produced in E. coli using Prokaryotic expression.
Background
ACVR1, also called ALK2 (Activin Receptor-Like Kinase 2), is a transmembrane serine/threonine kinase receptor. It binds ligands like BMPs (Bone Morphogenetic Proteins), initiating intracellular SMAD signaling. This receptor plays a crucial role in bone development, embryogenesis, and organogenesis. Mutations in ACVR1 are linked to fibrodysplasia ossificans progressiva (FOP), a rare disorder where soft tissues progressively ossify. Structurally, it comprises an extracellular ligand-binding domain, a single transmembrane helix, and an intracellular kinase domain.
Características del producto
category
Proteins and Peptides
origin
Human
host
E. coli
immunogen target
Activin A Receptor Type I (ACVR1)
host
E. coli
conjugation
Unconjugated
form
Lyophilized
tested applications
WB, SDS-PAGE
size 1
10 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
1 mg
expression
Recombinant
purity
> 95%
buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
or code
ACVR1
dry ice
No
availability
Shipped within 5-12 working days.
alias
ACVRLK2
uniprot id
note
This product is for research use only. <p></p> Not for human consumption, cosmetic, therapeutic or diagnostic use.
Quizá le pueda interesar
Activin Receptor Type-1 (ACVR1) Antibody
![Activin Receptor Type-1 (ACVR1) Antibody](/_next/image?url=https%3A%2F%2Fwww.abbexa.com%2Fimage%2Fcache%2Fdata%2Fproducts%2F18A%2Fabx007020_1_WB-500x500.jpg&w=3840&q=75)
proveedor
Abbexareference
abx007020Tested Applications
WBreactivity
Human, Mousestatus
RUOclonality
PolyclonalACVR1 Antibody is a Rabbit Polyclonal Antibody against ACVR1.
175€ (20 µl)
Ver másActivin Receptor Type-1 (Acvr1) Antibody
![Activin Receptor Type-1 (Acvr1) Antibody](/_next/image?url=https%3A%2F%2Fwww.abbexa.com%2Fimage%2Fcache%2Fdata%2Fproducts%2F10%2Fabx027611_Mouse_Acvr1_Antibody_WB_1-500x500.jpg&w=3840&q=75)
proveedor
Abbexareference
abx027611Tested Applications
ELISA, WB, IHCreactivity
Human, Mousestatus
RUOclonality
PolyclonalOn ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kina...
281.25€ (80 µl)
Ver másActivin Receptor Type-1 (ACVR1) Antibody
![Activin Receptor Type-1 (ACVR1) Antibody](/_next/image?url=https%3A%2F%2Fwww.abbexa.com%2Fimage%2Fcache%2Fdata%2Fproducts%2F10%2Fabx027646_ACVR1_Antibody_WB_1-500x500.jpg&w=3840&q=75)
proveedor
Abbexareference
abx027646Tested Applications
ELISA, WBreactivity
Humanstatus
RUOclonality
PolyclonalActivins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) s...
281.25€ (80 µl)
Ver más