Human Activin A Receptor Type 2B (ACVR2B) Protein (Active)
208€ (10 µg)
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name
Human Activin A Receptor Type 2B (ACVR2B) Protein (Active)
category
Proteins and Peptides
provider
Abbexa
reference
abx691382
tested applications
SDS-PAGE
Description
Human Activin Receptor 2B Protein is a recombinant protein from Human produced in Human Cells. Recombinant Human Activin Receptor Type 2B is produced by our Mammalian expression system and the target gene encoding Ser19-Thr134 is expressed with a Fc, 6His tag at the C-terminus.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Activin Receptor 2B |
| Host | Human |
| Origin | Human |
| Observed MW | Molecular Weight: 41.3 kDa Sequence Fragment: Ser19-Thr134 Tag: C-terminal Fc tag and 6 His tag |
| Expression | Recombinant |
| Purity | > 95% (SDS-PAGE) |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Form | Lyophilized |
| Tested Applications | SDS-PAGE |
| Buffer | 20mM PB, 150mM NaCl, pH7.4. |
| Availability | Shipped within 5-15 working days. |
| Storage | Store at < -20°C. |
| Dry Ice | No |
| UniProt ID | Q13705 |
| Alias | Activin receptor type IIB,ACTR-IIB |
| Background | Protein ACVR2B |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
ACVR2B is another type II receptor involved in activin and myostatin signaling pathways. It phosphorylates type I receptors (e.g., ACVR1B) to activate SMAD-dependent signaling cascades. ACVR2B regulates processes like muscle growth, reproductive function, and embryonic development. Inhibition of ACVR2B has been explored as a therapeutic approach for muscle-wasting disorders, such as cachexia and muscular dystrophy. Mutations in ACVR2B can impair ligand-receptor interactions, leading to developmental defects.
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