Human Activin A Receptor Type 2A (ACVR2A) Protein

Este producto es parte de ACVR - Activin A Receptor Type
Human Activin A Receptor Type 2A (ACVR2A) Protein
234€ (10 µg)

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Name
Human Activin A Receptor Type 2A (ACVR2A) Protein
Category
Proteins and Peptides
Provider
Abbexa
Reference
abx065140
Tested Applications
WB, SDS-PAGE

Description

Human Activin A Receptor Type II A (ACVR2A) is a recombinant Human protein expressed in E. coli.

Documentos del producto

Instrucciones
Data sheet
Descargar

Especificaciones del producto

Category
Proteins and Peptides
Immunogen Target
Activin A Receptor Type 2A (ACVR2A)
Host
E. coli
Assay Type
Activity: Not tested
Sequence Fragment: Ala20-Pro135
Tag: N-terminal His tag and GST tag
Origin
Human
Conjugation
Unconjugated
Observed MW
Calculated MW: 40.5 kDa
Expression
Recombinant
Purity
> 95%
Size 1
10 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
500 µg
Form
Lyophilized
Tested Applications
WB, SDS-PAGE
Buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
Availability
Shipped within 5-7 working days.
Storage
Store lyophilized form at 2-8°C for up to 1 month. For longer periods, store lyophilized or liquid at -80°C. Avoid repeated freeze–thaw cycles.
Dry Ice
No
UniProt ID
P27037
Alias
ACVR2,Activin receptor type II,ACTR-IIA
Background
Protein ACVR2A
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
Concentration: Prior to lyophilization: 200 µg/ml

Background

ACVR2A is a type II receptor that binds activin ligands and subsequently activates type I receptors like ACVR1B. This receptor is integral to TGF-β/activin signaling, mediating cellular processes like growth, differentiation, and apoptosis. ACVR2A is expressed in various tissues, particularly in the reproductive system. Mutations or loss of ACVR2A function are implicated in cancers such as colorectal carcinoma, where its absence disrupts normal cell cycle control and promotes tumor progression.

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