935106861
info@markelab.com
Precio
618.75€ (96 tests)
Human Activin A Receptor Type 1 (ACVR1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Activin A Receptor Type 1 (ACVR1) concentrations in tissue homogenates and other biological fluids. This assay has high sensitivity and excellent specificity for detection of ACVR1 (ACVR1)No significant cross-reactivity or interference between ACVR1 (ACVR1) and analogues was observed.
ACVR1, also called ALK2 (Activin Receptor-Like Kinase 2), is a transmembrane serine/threonine kinase receptor. It binds ligands like BMPs (Bone Morphogenetic Proteins), initiating intracellular SMAD signaling. This receptor plays a crucial role in bone development, embryogenesis, and organogenesis. Mutations in ACVR1 are linked to fibrodysplasia ossificans progressiva (FOP), a rare disorder where soft tissues progressively ossify. Structurally, it comprises an extracellular ligand-binding domain, a single transmembrane helix, and an intracellular kinase domain.
ELISA Kits
Activin A Receptor Type 1 (ACVR1)
Human
0.156 ng/ml - 10 ng/ml
< 0.06 ng/ml
Sandwich
Quantitative
Colorimetric
Tissue homogenates,Other biological fluids
96 tests
5 × 96 tests
10 × 96 tests
ACVRLK2
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
ACVR1
No
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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