Human Activin A Receptor Type 1 (ACVR1) CLIA Kit
![Human Activin A Receptor Type 1 (ACVR1) CLIA Kit](/_next/image?url=https%3A%2F%2Fmarkelab.com%2Fpublic-files%2Fimages%2FELISA-box.webp&w=3840&q=75)
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935106861
info@markelab.com
Precio
812.5€ (96 tests)
CLIA Kits ACVR1
proveedor
Abbexareference
abx492278Tested Applications
CLIAreactivity
Humanstatus
RUOclonality
Descripción
Human ACVR1 Chemiluminescent Immunoassay (CLIA) Kit is a Sandwich Chemiluminescent Immunoassay (CLIA) Kit for use with Tissue homogenates, cell lysates and other biological fluids.
Human ACVR1 CLIA Kit es un kit CLIA tipo Sandwich para su uso con homogeneizados de tejido, lisados celulares y otros fluidos biológicos.
Background
ACVR1, also called ALK2 (Activin Receptor-Like Kinase 2), is a transmembrane serine/threonine kinase receptor. It binds ligands like BMPs (Bone Morphogenetic Proteins), initiating intracellular SMAD signaling. This receptor plays a crucial role in bone development, embryogenesis, and organogenesis. Mutations in ACVR1 are linked to fibrodysplasia ossificans progressiva (FOP), a rare disorder where soft tissues progressively ossify. Structurally, it comprises an extracellular ligand-binding domain, a single transmembrane helix, and an intracellular kinase domain.
Características del producto
category
CLIA Kits
immunogen target
Activin A Receptor Type 1 (ACVR1)
reactivity
Human
test range
0.156 ng/ml - 10 ng/ml
sensitivity
< 0.063 ng/ml
assay type
Sandwich
assay data
Quantitative
detection method
Chemiluminescent
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
size 2
5 × 96 tests
size 3
10 × 96 tests
alias
ACVRLK2
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
ACVR1
dry ice
No
uniprot id
note
El rango y la sensibilidad pueden variar. Le recomendamos contactar con nosotros a fin de obtener la última información sobre posibles actualizaciones, que no estén representadas en este catalogo. Si necesita un rango específico, contáctenos y trataremos de ayudarle. Consulte sobre posible información que pueda ayudarle a elegir la dilución apropiada para sus muestras. Los kits CLIA están optimizados para la detección de muestras nativas, las proteínas recombinantes, pueden resultar problemáticas a causa de diferencias en la secuencia o cambios en la estructura terciaria.
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