Human Actinin Alpha 3 (ACTN3) Protein

221€ (10 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Human Actinin Alpha 3 (ACTN3) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx167185
tested applications
WB, SDS-PAGE
Description
Actinin Alpha 3 Protein is a recombinant Human protein expressed in E. coli.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Proteins and Peptides |
Immunogen Target | Actinin Alpha 3 (ACTN3) |
Host | E. coli |
Origin | Human |
Conjugation | Unconjugated |
Observed MW | Molecular Weight: Calculated MW: 33.8 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Glu162-Lys416 Tag: N-terminal His tag |
Expression | Recombinant |
Purity | > 97% |
Size 1 | 10 µg |
Size 2 | 50 µg |
Size 3 | 100 µg |
Size 4 | 200 µg |
Size 5 | 500 µg |
Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
Tested Applications | WB, SDS-PAGE |
Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
Availability | Shipped within 5-7 working days. |
Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
Alias | ACTN3D |
Background | Protein ACTN3 |
Status | RUO |
Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
ACTN3 encodes alpha-actinin-3, a protein primarily expressed in fast-twitch skeletal muscle fibers, where it contributes to muscle strength and power. Unlike its closely related isoform ACTN2, ACTN3 is specialized for rapid and forceful contractions, playing a structural role in maintaining sarcomeric integrity and optimizing muscle performance. A common polymorphism in the ACTN3 gene results in the absence of alpha-actinin-3 in a significant proportion of the population, which has been associated with variations in muscle performance. The "null" variant is linked to reduced muscle power but enhanced endurance, reflecting its evolutionary role in adapting to physical demands. ACTN3 is crucial in regulating the balance between muscle power and endurance, with implications in athletic performance, muscle health, and susceptibility to muscle-related disorders.
Related Products

Human ACTN3 (Alpha-actinin-3) ELISA Kit
Ver Producto
ACTN3 antibody
F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein.
Ver Producto
ACTN3 antibody
F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein.
Ver Producto