Human Actinin Alpha 3 (ACTN3) CLIA Kit
643.5€ (96 tests)
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name
Human Actinin Alpha 3 (ACTN3) CLIA Kit
category
CLIA Kits
provider
Abbexa
reference
abx195088
tested applications
CLIA
Description
Human Actinin Alpha 3 (ACTN3) Chemiluminescent Immunoassay (CLIA) Kit is a Chemiluminescent Immunoassay (CLIA) kit against Actinin Alpha 3 (ACTN3).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | CLIA Kits |
| Immunogen Target | Actinin Alpha 3 (ACTN3) |
| Reactivity | Human |
| Detection Method | Chemiluminescent |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 78 pg/ml - 5000 pg/ml |
| Sensitivity | 46.9 pg/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | CLIA |
| Sample Type | Serum, plasma and other biological fluids. |
| Availability | Shipped within 5-12 working days. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| Alias | ACTN3D |
| Background | CLIA Kits ACTN3 |
| Status | RUO |
| Note | The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
ACTN3 encodes alpha-actinin-3, a protein primarily expressed in fast-twitch skeletal muscle fibers, where it contributes to muscle strength and power. Unlike its closely related isoform ACTN2, ACTN3 is specialized for rapid and forceful contractions, playing a structural role in maintaining sarcomeric integrity and optimizing muscle performance. A common polymorphism in the ACTN3 gene results in the absence of alpha-actinin-3 in a significant proportion of the population, which has been associated with variations in muscle performance. The "null" variant is linked to reduced muscle power but enhanced endurance, reflecting its evolutionary role in adapting to physical demands. ACTN3 is crucial in regulating the balance between muscle power and endurance, with implications in athletic performance, muscle health, and susceptibility to muscle-related disorders.
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