Human Actin Related Protein 3 (ACTR3) Protein

208€ (10 µg)
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935106861
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name
Human Actin Related Protein 3 (ACTR3) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx652259
tested applications
WB, SDS-PAGE
Description
Actin Related Protein 3 (ACTR3) Protein is a Recombinant protein from Human.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Proteins and Peptides |
Immunogen Target | Actin Related Protein 3 (ACTR3) |
Host | E. coli |
Origin | Human |
Conjugation | Unconjugated |
Observed MW | Molecular Weight: Calculated MW: 31.7 kDa Observed MW (SDS-PAGE): 32 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Pro6-Lys254 Tag: N-terminal His tag |
Expression | Recombinant |
Purity | > 95% |
Size 1 | 10 µg |
Size 2 | 50 µg |
Size 3 | 100 µg |
Size 4 | 200 µg |
Size 5 | 500 µg |
Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 20 mM Tris, 150 mM NaCl, pH 8.0. If a higher concentration is required, the product can be reconstituted directly in 20 mM Tris, 150 mM NaCl, pH 8.0, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
Tested Applications | WB, SDS-PAGE |
Buffer | Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 1 mM EDTA, 1 mM DTT, 0.01% Sarcosyl, 5% Trehalose and Proclin-300. |
Availability | Shipped within 5-7 working days. |
Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
Alias | ACTR3,ARP3 |
Background | Protein ACTR3 |
Status | RUO |
Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
ACTR3 functions alongside ACTR2 as part of the ARP2/3 complex, driving actin filament branching and nucleation. Structurally, ACTR3 forms a dimer with ACTR2 to create a template for new filament growth. It plays a fundamental role in cytoskeletal remodeling processes, such as cell motility, intracellular trafficking, and immune cell function. ACTR3 is indispensable for processes like lamellipodia extension during cell migration. Mutations in ACTR3 are linked to developmental abnormalities, immune deficiencies, and impaired wound healing due to defective actin polymerization.
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