Actin Related Protein 3 (ACTR3) Antibody

Este producto es parte de ACTR - Actin related protein
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292.5€ (80 µl)

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935106861
info@markelab.com
name
Actin Related Protein 3 (ACTR3) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx031774
tested applications
ELISA, WB, IHC, FCM

Description

ACTR3 is known to be a major constituent of the ARP2/3 complex. This complex is located at the cell surface and is essential to cell shape and motility through lamellipodial actin assembly and protrusion.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
Actin Related Protein 3 (ACTR3)
Host
Rabbit
Reactivity
Human
Recommended Dilution
WB: 1/1000, IHC-P: 1/50 - 1/100, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Purified Rabbit Polyclonal Antibody.
Size 1
80 µl
Size 2
400 µl
Form
Liquid
Tested Applications
ELISA, WB, IHC, FCM
Buffer
PBS containing 0.09% sodium azide.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P61158
Alias
ACTR3,ARP3
Background
Antibody anti-ACTR3
Status
RUO

Descripción

ACTR3 functions alongside ACTR2 as part of the ARP2/3 complex, driving actin filament branching and nucleation. Structurally, ACTR3 forms a dimer with ACTR2 to create a template for new filament growth. It plays a fundamental role in cytoskeletal remodeling processes, such as cell motility, intracellular trafficking, and immune cell function. ACTR3 is indispensable for processes like lamellipodia extension during cell migration. Mutations in ACTR3 are linked to developmental abnormalities, immune deficiencies, and impaired wound healing due to defective actin polymerization.

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