Human Acidic Leucine-Rich Nuclear Phosphoprotein 32 Family Member B (ANP32B) ELISA Kit
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Description
Human Acidic Leucine-Rich Nuclear Phosphoprotein 32 Family Member B (ANP32B) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Acidic Nuclear Phosphoprotein 32 Family Member B (ANP32B) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Acidic Leucine-Rich Nuclear Phosphoprotein 32 Family Member B (ANP32B) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.312 ng/ml - 20 ng/ml |
| Sensitivity | < 0.14 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q92688 |
| Gene ID | 10541 |
| Alias | ANP32B,APRIL,PHAPI2 |
| Background | Elisa kits for ANP32B |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
ANP32B is a nuclear phosphoprotein that shares structural and functional similarities with ANP32A, particularly in chromatin regulation and RNA processing. ANP32B functions as a regulator of apoptosis, cell proliferation, and gene transcription, making it critical for cellular homeostasis and growth control. It is essential for embryonic development, with knockout studies indicating its requirement for cell survival and proper organogenesis. ANP32B also modulates the activity of HDAC complexes, contributing to histone deacetylation and transcriptional repression. Dysregulation of ANP32B has been linked to cancer progression and metastasis, where it promotes cell proliferation and resistance to apoptosis. Its involvement in multiple pathways underscores its importance as a potential therapeutic target in oncology.
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Human ANP32B (Acidic leucine-rich nuclear phosphoprotein 32 family member B) ELISA Kit
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Multifunctional protein working as a cell cycle progression factor as well as a cell survival factor. Required for the progression from the G1 to the S phase. Anti-apoptotic protein which functions as a caspase-3 inhibitor. Has no phosphatase 2A(PP2A) inhibitor activity(By similarity). Exhibits histone chaperone properties, stimulating core histones to assemble into a nucleosome.
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Multifunctional protein working as a cell cycle progression factor as well as a cell survival factor. Required for the progression from the G1 to the S phase. Anti-apoptotic protein which functions as a caspase-3 inhibitor. Has no phosphatase 2A(PP2A) inhibitor activity(By similarity). Exhibits histone chaperone properties, stimulating core histones to assemble into a nucleosome.
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