Human 1-Acylglycerol-3-Phosphate O-Acyltransferase ABHD5 (ABHD5) ELISA Kit
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Description
Human 1-Acylglycerol-3-Phosphate O-Acyltransferase ABHD5 (ABHD5) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human 1-Acylglycerol-3-Phosphate O-Acyltransferase ABHD5 (ABHD5) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Product specifications
| Category | ELISA Kits |
| Immunogen Target | 1-Acylglycerol-3-Phosphate O-Acyltransferase ABHD5 (ABHD5) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Sensitivity | < 0.06 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q8WTS1 |
| Gene ID | 51099 |
| OMIM | 275630 |
| Alias | CGI58,IECN2,NCIE2 |
| Background | Elisa kits for ABHD5 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
ABHD5, also known as CGI-58, is a critical coactivator of adipose triglyceride lipase (ATGL), a key enzyme in lipolysis. It promotes the hydrolysis of triglycerides into glycerol and free fatty acids, thereby regulating lipid storage and energy metabolism. ABHD5 is highly expressed in adipose tissue, liver, and muscles, where it plays an essential role in lipid mobilization and energy balance. Mutations in the ABHD5 gene are associated with Chanarin-Dorfman syndrome, a rare lipid storage disorder characterized by excessive lipid accumulation in various tissues. Beyond lipolysis, ABHD5 influences lipid signaling pathways and cellular lipid composition, affecting processes such as inflammation and metabolic homeostasis. Dysregulation of ABHD5 activity can contribute to obesity, insulin resistance, and other metabolic syndromes, highlighting its critical role in energy regulation and lipid metabolism.
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