Human 1-Acylglycerol-3-Phosphate O-Acyltransferase ABHD5 (ABHD5) ELISA Kit
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935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for ABHD5
proveedor
Abbexareference
abx385556Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human 1-Acylglycerol-3-Phosphate O-Acyltransferase ABHD5 (ABHD5) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human 1-Acylglycerol-3-Phosphate O-Acyltransferase ABHD5 (ABHD5) concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
ABHD5, also known as CGI-58, is a critical coactivator of adipose triglyceride lipase (ATGL), a key enzyme in lipolysis. It promotes the hydrolysis of triglycerides into glycerol and free fatty acids, thereby regulating lipid storage and energy metabolism. ABHD5 is highly expressed in adipose tissue, liver, and muscles, where it plays an essential role in lipid mobilization and energy balance. Mutations in the ABHD5 gene are associated with Chanarin-Dorfman syndrome, a rare lipid storage disorder characterized by excessive lipid accumulation in various tissues. Beyond lipolysis, ABHD5 influences lipid signaling pathways and cellular lipid composition, affecting processes such as inflammation and metabolic homeostasis. Dysregulation of ABHD5 activity can contribute to obesity, insulin resistance, and other metabolic syndromes, highlighting its critical role in energy regulation and lipid metabolism.
Características del producto
category
ELISA Kits
immunogen target
1-Acylglycerol-3-Phosphate O-Acyltransferase ABHD5 (ABHD5)
reactivity
Human
test range
0.156 ng/ml - 10 ng/ml
sensitivity
< 0.06 ng/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
CGI58,IECN2,NCIE2
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
ABHD5
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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