Human Abhydrolase Domain Containing 2 (ABHD2) ELISA Kit

Este producto es parte de ABHD - Abhydrolase Domain Containing
Human Abhydrolase Domain Containing 2 (ABHD2) ELISA Kit

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935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for ABHD2

proveedor

Abbexa

reference

abx385555

Tested Applications

ELISA

reactivity

Human

status

RUO

clonality

Descripción

Human Abhydrolase Domain Containing 2 (ABHD2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Abhydrolase Domain Containing 2 (ABHD2) concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

ABHD2 is a serine hydrolase well-known for its role in sperm activation and fertilization by regulating the CatSper calcium channel, which is activated by progesterone. This calcium influx is essential for sperm motility and the acrosome reaction. Beyond reproduction, ABHD2 is expressed in the lungs, brain, and immune cells, where it hydrolyzes bioactive lipids, including 2-arachidonoylglycerol (2-AG), a key endocannabinoid. Through lipid metabolism, ABHD2 modulates inflammatory responses, immune signaling, and cellular lipid composition. Dysregulation of ABHD2 has been associated with infertility, due to impaired sperm activation, and inflammatory diseases, highlighting its dual importance in reproductive biology and immune regulation. Structurally, ABHD2 features a catalytic triad within its hydrolase domain, driving its activity in lipid processing and signaling. Its multifunctionality and therapeutic relevance make it a critical target for understanding lipid metabolism in both reproductive and systemic contexts.

Características del producto

category

ELISA Kits


immunogen target

Abhydrolase Domain Containing 2 (ABHD2)


reactivity

Human


test range

0.313 ng/ml - 20 ng/ml


sensitivity

< 0.19 ng/ml


assay type

Sandwich


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


size 2

5 × 96 tests


size 3

10 × 96 tests


alias

HS1-2,LABH2,PHPS1-2


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

ABHD2


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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