Human A Disintegrin And Metalloproteinase With Thrombospondin 9 (ADAMTS9) Protein

Este producto es parte de ADAMTS9 - ADAM metallopeptidase with thrombospondin type 1 motif 9
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221€ (10 µg)

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935106861
info@markelab.com
name
Human A Disintegrin And Metalloproteinase With Thrombospondin 9 (ADAMTS9) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx166542
tested applications
WB, SDS-PAGE

Description

ADAMTS9 Protein is a recombinant Human protein expressed in E. coli.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Proteins and Peptides
Immunogen Target
A Disintegrin And Metalloproteinase With Thrombospondin 9 (ADAMTS9)
Host
E. coli
Origin
Human
Conjugation
Unconjugated
Observed MW
Molecular Weight: Calculated MW: 26.8 kDa  Observed MW (SDS-PAGE): 27 kDa
Concentration: Prior to lyophilization: 200 µg/ml
Sequence Fragment: Cys1727-Leu1935
Tag: N-terminal His tag
Expression
Recombinant
Purity
> 80%
Size 1
10 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
500 µg
Form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 20 mM Tris, 150 mM NaCl, pH 8.0. If a higher concentration is required, the product can be reconstituted directly in 20 mM Tris, 150 mM NaCl, pH 8.0, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
Tested Applications
WB, SDS-PAGE
Buffer
Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 1 mM EDTA, 1 mM DTT, 0.01% Sarcosyl, 5% Trehalose and Proclin-300.
Availability
Shipped within 5-7 working days.
Storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
Dry Ice
No
Alias
KIAA1312, Type 1 Motif 9,A Disintegrin And Metalloproteinase With Thrombospondin Motifs 9,ADAMTS-9,ADAM-TS9
Background
Protein ADAMTS9
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

ADAMTS9 (A Disintegrin And Metalloproteinase with Thrombospondin Motifs 9) is a member of the ADAMTS family of proteases. Like other members of the ADAMTS family, ADAMTS9 contains characteristic domains, including a metalloproteinase domain, a disintegrin-like domain, and thrombospondin type-1 (TSP-1) motifs. ADAMTS9 is expressed in various tissues, including the brain, heart, kidney, cartilage, and skeletal muscle. Its expression pattern suggests potential roles in tissue development, maintenance, and remodeling.ADAMTS9 is involved in various physiological processes, particularly in extracellular matrix (ECM) remodeling. It plays a role in the turnover and organization of ECM components, such as proteoglycans and collagens. Additionally, ADAMTS9 has been implicated in angiogenesis, wound healing, and inflammation.Dysregulation of ADAMTS9 has been associated with several diseases and conditions. For instance, ADAMTS9 has been linked to cancer, where it may affect tumor growth, invasion, and metastasis by influencing the ECM and angiogenesis. Moreover, mutations in the ADAMTS9 gene have been associated with certain developmental disorders and connective tissue diseases.

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