Human A Disintegrin And Metalloproteinase With Thrombospondin 9 (ADAMTS9) Protein

221€ (10 µg)
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935106861
info@markelab.com
name
Human A Disintegrin And Metalloproteinase With Thrombospondin 9 (ADAMTS9) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx166542
tested applications
WB, SDS-PAGE
Description
ADAMTS9 Protein is a recombinant Human protein expressed in E. coli.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Proteins and Peptides |
Immunogen Target | A Disintegrin And Metalloproteinase With Thrombospondin 9 (ADAMTS9) |
Host | E. coli |
Origin | Human |
Conjugation | Unconjugated |
Observed MW | Molecular Weight: Calculated MW: 26.8 kDa Observed MW (SDS-PAGE): 27 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Cys1727-Leu1935 Tag: N-terminal His tag |
Expression | Recombinant |
Purity | > 80% |
Size 1 | 10 µg |
Size 2 | 50 µg |
Size 3 | 100 µg |
Size 4 | 200 µg |
Size 5 | 500 µg |
Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 20 mM Tris, 150 mM NaCl, pH 8.0. If a higher concentration is required, the product can be reconstituted directly in 20 mM Tris, 150 mM NaCl, pH 8.0, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
Tested Applications | WB, SDS-PAGE |
Buffer | Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 1 mM EDTA, 1 mM DTT, 0.01% Sarcosyl, 5% Trehalose and Proclin-300. |
Availability | Shipped within 5-7 working days. |
Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
Alias | KIAA1312, Type 1 Motif 9,A Disintegrin And Metalloproteinase With Thrombospondin Motifs 9,ADAMTS-9,ADAM-TS9 |
Background | Protein ADAMTS9 |
Status | RUO |
Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
ADAMTS9 (A Disintegrin And Metalloproteinase with Thrombospondin Motifs 9) is a member of the ADAMTS family of proteases. Like other members of the ADAMTS family, ADAMTS9 contains characteristic domains, including a metalloproteinase domain, a disintegrin-like domain, and thrombospondin type-1 (TSP-1) motifs. ADAMTS9 is expressed in various tissues, including the brain, heart, kidney, cartilage, and skeletal muscle. Its expression pattern suggests potential roles in tissue development, maintenance, and remodeling.ADAMTS9 is involved in various physiological processes, particularly in extracellular matrix (ECM) remodeling. It plays a role in the turnover and organization of ECM components, such as proteoglycans and collagens. Additionally, ADAMTS9 has been implicated in angiogenesis, wound healing, and inflammation.Dysregulation of ADAMTS9 has been associated with several diseases and conditions. For instance, ADAMTS9 has been linked to cancer, where it may affect tumor growth, invasion, and metastasis by influencing the ECM and angiogenesis. Moreover, mutations in the ADAMTS9 gene have been associated with certain developmental disorders and connective tissue diseases.
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