Human A Disintegrin And Metalloprotease 28 (ADAM28) Protein

Pida mas información
935106861
info@markelab.com
Precio
234€ (10 µg)
Protein ADAM28
proveedor
Abbexareference
abx065061Tested Applications
WB, SDS-PAGEreactivity
status
RUOclonality
Descripción
Recombinant ADAM28 is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).
Background
ADAM28 (A Disintegrin And Metalloproteinase domain-containing protein 28) is a member of the ADAM (a disintegrin and metalloproteinase) family of proteins. Like other members of this family, ADAM28 contains several distinct domains, including a metalloproteinase domain, a disintegrin domain, a cysteine-rich domain, an EGF-like domain, a transmembrane domain, and a cytoplasmic tail. These domains confer diverse functions to ADAM28, including proteolytic activity, cell adhesion, cell signaling, and regulation of protein-protein interactions.ADAM28 is primarily expressed in the testis, but it is also found in other tissues such as the spleen, lymph nodes, and thymus. In addition to its presence in normal tissues, ADAM28 expression has been detected in certain pathological conditions, including various cancers such as breast cancer, ovarian cancer, and prostate cancer. Its expression in these cancers suggests potential roles in tumor progression, invasion, and metastasis.ADAM28 has been implicated in immune responses and inflammatory processes. It is expressed in immune cells such as macrophages and dendritic cells, where it may participate in cell-cell interactions, cytokine signaling, and immune cell activation.
Características del producto
category
Proteins and Peptides
origin
Human
host
E. coli
immunogen target
A Disintegrin And Metalloprotease 28 (ADAM28)
host
E. coli
conjugation
Unconjugated
form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 20 mM Tris, 150 mM NaCl, pH 8.0. If a higher concentration is required, the product can be reconstituted directly in 20 mM Tris, 150 mM NaCl, pH 8.0, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
tested applications
WB, SDS-PAGE
size 1
10 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
500 µg
observerd MW
Molecular Weight: Calculated MW: 29.3 kDa Observed MW (SDS-PAGE): 34 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Glu525-Lys774 Tag: N-terminal His tag
expression
Recombinant
purity
> 97%
buffer
Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 1 mM EDTA, 1 mM DTT, 0.01% Sarcosyl, 5% Trehalose and Proclin-300.
storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
or code
ADAM28
dry ice
No
availability
Shipped within 5-7 working days.
alias
EMDCII, MDC-Lm, MDC-Ls,Cysteine-Rich Protein II,MDCL,adam-28
uniprot id
note
This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.
Quizá le pueda interesar
Human ADAM28(Disintegrin and metalloproteinase domain-containing protein 28) ELISA Kit

proveedor
FineTestreference
EH1628reactivity
humanstatus
RUOPrecio a consultar
Ver másMouse Adam28(Disintegrin and metalloproteinase domain-containing protein 28) ELISA Kit

proveedor
FineTestreference
EM0613reactivity
mousestatus
RUOPrecio a consultar
Ver másanti- ADAM28 antibody

proveedor
FineTestreference
FNab00142Tested Applications
ELISA, WBreactivity
human,mouse,ratstatus
RUOclonality
polyclonalMay play a role in the adhesive and proteolytic events that occur during lymphocyte emigration or may function in ectodo...
Precio a consultar
Ver más