Human 26S Proteasome Non-ATPase Regulatory Subunit 11 (PSMD11) Protein
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Description
26S Proteasome Non-ATPase Regulatory Subunit 11 (PSMD11) is a recombinant enzyme. The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a member of the proteasome subunit S9 family that functions as a non-ATPase subunit of the 19S regulator and is phosphorylated by AMP-activated protein kinase. Alternatively spliced transcript variants have been observed for this gene.
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Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | 26S Proteasome Non-ATPase Regulatory Subunit 11 (PSMD11) |
| Host | E. coli |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Origin | Human |
| Expression | Recombinant |
| Purity | > 85% (SDS-PAGE) |
| Size 1 | 5 µg |
| Size 2 | 25 µg |
| Size 3 | 1 mg |
| Form | Liquid |
| Tested Applications | SDS-PAGE |
| Availability | Shipped within 5-10 working days. |
| Storage | Store at 4 °C if the entire vial will be used within 2-4 weeks. Store at -20 °C for long term storage. For long term storage, it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O00231 |
| Gene ID | 5717 |
| NCBI Accession | NP_001257411.1, NM_001270482.1, [O00231-1], NP_002806.2, NM_002815.3, [O00231-1] |
| OMIM | 604449 |
| Background | Protein PSMD11 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
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