Horse PLAU(Urokinase-Type Plasminogen Activator) ELISA Kit
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Product specifications
| Category | ELISA Kits |
| Reactivity | horse |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich ELISA, Double Antibody |
| Test Range | 62.5-4000pg/ml |
| Size 1 | 96T |
| Sample Type | Serum,Plasma,Tissue homogenates,Other biological fluids |
| Availability | Shipped within 10-14 working days. |
| Storage | 2-8 °C for 6 months |
| UniProt ID | F7BT48 |
| Alias | uPA|PLAU|Urokinase|ATF|plasminogen activator|urokinase|UPA|u-PA|U-plasminogen activator|urinary|urokinase-type plasminogen activator |
| Background | Elisa Kits PLAU |
| Status | RUO |
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Urokinase-Type Plasminogen Activator (PLAU) Antibody
PLAU Antibody is a Rabbit Polyclonal antibody against PLAU. This gene encodes a serine protease involved in degradation of the extracellular matrix and possibly tumor cell migration and proliferation. A specific polymorphism in this gene may be associated with late-onset Alzheimer's disease and also with decreased affinity for fibrin-binding. This protein converts plasminogen to plasmin by specific cleavage of an Arg-Val bond in plasminogen. Plasmin in turn cleaves this protein at a Lys-Ile bond to form a two-chain derivative in which a single disulfide bond connects the amino-terminal A-chain to the catalytically active, carboxy-terminal B-chain. This two-chain derivative is also called HMW-uPA (high molecular weight uPA). HMW-uPA can be further processed into LMW-uPA (low molecular weight uPA) by cleavage of chain A into a short chain A (A1) and an amino-terminal fragment. LMW-uPA is proteolytically active but does not bind to the uPA receptor. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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