Horse Leptin (LEP) Protein

Pida mas información
935106861
info@markelab.com
Precio
403€ (50 µg)
Protein LEP
proveedor
Abbexareference
abx067743Tested Applications
WB, SDS-PAGEreactivity
status
RUOclonality
Descripción
Recombinant Leptin (LEP) is a recombinant Horse protein produced in a Prokaryotic expression system (E. coli).
Background
Leptin ( LEP) is an adipokine predominantly produced by adipocytes that plays a key role in regulating energy balance, appetite, and metabolism by acting on the hypothalamus Leptin signals through its receptor (LEPR) to suppress food intake and promote energy expenditure, maintaining body weight homeostasis Circulating leptin levels are proportional to fat mass, with increased levels observed in obesity due to leptin resistance Dysregulation of leptin signaling is associated with metabolic syndrome, type 2 diabetes, and cardiovascular diseases Leptin also exerts immunomodulatory functions, influencing the activity of T cells, macrophages, and other immune cells to enhance pro-inflammatory responses It is implicated in autoimmune diseases, including rheumatoid arthritis and lupus, where elevated leptin promotes chronic inflammation Leptin’s role extends to bone metabolism, reproductive function, and wound healing, highlighting its pleiotropic effects in energy homeostasis and systemic physiology
Características del producto
category
Proteins and Peptides
origin
Horse
host
E. coli
immunogen target
Leptin (LEP)
host
E. coli
conjugation
Unconjugated
form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
tested applications
WB, SDS-PAGE
size 1
50 µg
size 2
100 µg
size 3
200 µg
size 4
500 µg
size 5
1 mg
observerd MW
Molecular Weight: Calculated MW: 17.7 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Ile15-Ala141 Tag: N-terminal His tag
expression
Recombinant
purity
> 95%
buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
or code
LEP
dry ice
No
availability
Shipped within 5-7 working days.
alias
OB,OBS,LEPD,Obese protein,Obesity factor
uniprot id
note
This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.
Quizá le pueda interesar
Bovine Lep(Leptin) ELISA Kit

proveedor
FineTestreference
EB0093reactivity
bovinestatus
RUOPrecio a consultar
Ver másChicken LEP(Leptin) ELISA Kit

proveedor
FineTestreference
ECH0079reactivity
chickenstatus
RUOPrecio a consultar
Ver másGoat LEP(Leptin) ELISA Kit

proveedor
FineTestreference
EG0042reactivity
goatstatus
RUOPrecio a consultar
Ver más