Horse Interleukin 4 (IL4) Protein

390€ (50 µg)
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name
Horse Interleukin 4 (IL4) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx654035
tested applications
WB, SDS-PAGE
Description
Horse Interleukin 4 (IL4) Protein is a Recombinant Horse protein expressed in E. coli.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Proteins and Peptides |
Immunogen Target | Interleukin 4 (IL4) |
Host | E. coli |
Origin | Horse |
Conjugation | Unconjugated |
Observed MW | Molecular Weight: Calculated MW: 16.4 kDa Observed MW (SDS-PAGE): 17 kDa Concentration: Prior to lyophilization: 100 µg/ml Sequence Fragment: Cys25-Cys137 Tag: N-terminal His tag |
Expression | Recombinant |
Purity | > 90% |
Size 1 | 50 µg |
Size 2 | 100 µg |
Size 3 | 200 µg |
Size 4 | 500 µg |
Size 5 | 1 mg |
Form | Lyophilized Reconstitute in ddH2O to a concentration of 0.1-1.0 mg/ml. Do not vortex. |
Tested Applications | WB, SDS-PAGE |
Buffer | Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 0.01% Sarcosyl, 5% Trehalose. |
Availability | Shipped within 5-12 working days. |
Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | A7LBR9 |
Alias | BSF1,IL-4,BCGF1,BSF-1,BCGF-1,B-cell stimulatory factor 1,Binetrakin,Lymphocyte stimulatory factor 1,Pitrakinra |
Background | Protein IL4 |
Status | RUO |
Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
Interleukin-4 (IL4) is a crucial cytokine in the immune system, primarily involved in the regulation of humoral (antibody-mediated) immune responses and the differentiation of immune cells. It is produced by several immune cells, including activated CD4+ T cells (specifically Th2 cells), mast cells, basophils, eosinophils, and, to a lesser extent, CD8+ T cells. IL-4 is a member of the interleukin family of cytokines and plays a key role in driving the differentiation of naïve helper T cells (Th0) into Th2 cells, which are central to the adaptive immune response. This cytokine is also vital in inducing B cell class switching to immunoglobulin E (IgE), a process essential for allergic reactions. In addition to its immune-regulatory functions, IL-4 is heavily involved in allergic diseases such as asthma, allergic rhinitis, and atopic dermatitis. IL-4 mediates a wide range of biological effects that contribute to inflammation, allergy, and immune system modulation.
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