HLA Class I Histocompatibility Antigen, Alpha Chain G (HLA-G) Antibody
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Description
HLA Class I Histocompatibility Antigen, Alpha Chain G (HLA-G) Antibody is a Recombinant Rabbit Monoclonal antibody for the detection of Human HLA-G.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | HLA Class I Histocompatibility Antigen, Alpha Chain G (HLA-G) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | FCM: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Expression | Recombinant |
| Purification | Purified by affinity chromatography. |
| Size 1 | 50 µl |
| Size 2 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, FCM |
| Buffer | PBS, pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P17693 |
| OMIM | 142871 |
| Background | Antibody anti-HLA-G |
| Status | RUO |
Descripción
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Human sHLA-G (soluble HLA class I histocompatibility antigen, alpha chain G) ELISA Kit
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HLA-G antibody
Human major histocompatibility complex (MHC) antigens, also referred to as human leukocyte antigens (HLA), are encoded by genes located on the short arm of chromosome 6 (6p21.3). HLA-G is a non-classical MHC class I molecule with multiple immunoregulatory properties. HLA-G exhibits a restricted pattern of expression that includes placental extravillous trophoblasts at the maternal-fetal interface, where it abolishes maternal immune cell activity against fetus and establishes immune tolerance. Aberrant expression of HLA-G has been found in a variety of human neoplastic diseases. It plays an important role in the escape of tumor cells from immunosurveillance.
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