Histone H2A Deubiquitinase MYSM2 (MYSM1) Antibody

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Description
MYSM1 Antibody is a Rabbit Polyclonal antibody against MYSM1. Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation.
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Product specifications
Category | Primary Antibodies |
Immunogen Target | Histone H2A Deubiquitinase MYSM2 (MYSM1) |
Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Recommended Dilution | ELISA: 1 µg/ml, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Purification | Purified by affinity chromatography. |
Size 1 | 20 µl |
Size 2 | 100 µl |
Size 3 | 2 × 100 µl |
Form | Liquid |
Tested Applications | ELISA, WB |
Buffer | PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol. |
Availability | Shipped within 5-10 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | Q5VVJ2 |
Gene ID | 114803 |
NCBI Accession | NP_001078956.1 |
Background | Antibody anti-MYSM1 |
Status | RUO |
Note | Concentration: > 0.2 mg/ml - |
Descripción
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