HIRA-Interacting Protein 3 (HIRIP3) Antibody

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Description
HIRIP3 Antibody is a Rabbit Polyclonal antibody against HIRIP3. The HIRA protein shares sequence similarity with Hir1p and Hir2p, the two corepressors of histone gene transcription characterized in the yeast, Saccharomyces cerevisiae. The structural features of the HIRA protein suggest that it may function as part of a multiprotein complex. Several cDNAs encoding HIRA-interacting proteins, or HIRIPs, have been identified. In vitro, the protein encoded by this gene binds HIRA, as well as H2B and H3 core histones, indicating that a complex containing HIRA-HIRIP3 could function in some aspects of chromatin and histone metabolism. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Documents del producto
Product specifications
| Category | Primary Antibodies  | 
| Immunogen Target | HIRA-Interacting Protein 3 (HIRIP3)  | 
| Host | Rabbit  | 
| Reactivity | Human, Mouse, Rat  | 
| Recommended Dilution | IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.  | 
| Clonality | Polyclonal  | 
| Conjugation | Unconjugated  | 
| Isotype | IgG  | 
| Purification | Purified by affinity chromatography.  | 
| Size 1 | 60 µl  | 
| Size 2 | 120 µl  | 
| Size 3 | 200 µl  | 
| Form | Liquid  | 
| Tested Applications | IHC, IF/ICC  | 
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.  | 
| Availability | Shipped within 5-10 working days.  | 
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.  | 
| Dry Ice | No  | 
| UniProt ID | Q9BW71  | 
| Gene ID | 8479  | 
| NCBI Accession | NP_003600.2  | 
| Background | Antibody anti-HIRIP3  | 
| Status | RUO  | 
| Note | Concentration: 1 mg/ml -  | 
Descripción
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HIRIP3 antibody
The HIRA protein shares sequence similarity with Hir1p and Hir2p, the two corepressors of histone gene transcription characterized in the yeast, Saccharomyces cerevisiae. The structural features of the HIRA protein suggest that it may function as part of a multiprotein complex. Several cDNAs encoding HIRA-interacting proteins, or HIRIPs, have been identified. In vitro, the protein encoded by this gene binds HIRA, as well as H2B and H3 core histones, indicating that a complex containing HIRA-HIRIP3 could function in some aspects of chromatin and histone metabolism. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
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HIRA-Interacting Protein 3 (HIRIP3) Antibody
HIRIP3 Antibody is a Rabbit Polyclonal antibody against HIRIP3. The HIRA protein shares sequence similarity with Hir1p and Hir2p, the two corepressors of histone gene transcription characterized in the yeast, Saccharomyces cerevisiae. The structural features of the HIRA protein suggest that it may function as part of a multiprotein complex. Several cDNAs encoding HIRA-interacting proteins, or HIRIPs, have been identified. In vitro, the protein encoded by this gene binds HIRA, as well as H2B and H3 core histones, indicating that a complex containing HIRA-HIRIP3 could function in some aspects of chromatin and histone metabolism. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
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The HIRA protein shares sequence similarity with Hir1p and Hir2p, the two corepressors of histone gene transcription characterized in the yeast, Saccharomyces cerevisiae. The structural features of the HIRA protein suggest that it may function as part of a multiprotein complex. Recently, several cDNAs encoding HIRA-interacting proteins, or HIRIPs, have been identified. In vitro, the HIRIP3 gene product binds HIRA, as well as H2B and H3 core histones, indicating that a complex containing HIRA-HIRIP3 could function in some aspects of chromatin and histone metabolism.
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