Heterochromatin-Associated Protein MENT (SERPINB10) Antibody

Este producto es parte de SERPINB10 - serpin family B member 10
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357.5€ (100 µg)

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935106861
info@markelab.com
name
Heterochromatin-Associated Protein MENT (SERPINB10) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx122213
tested applications
ELISA, WB, IHC

Description

Rabbit Polyclonal against the SERPINB10 protein.

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryPrimary Antibodies
Immunogen TargetHeterochromatin-Associated Protein MENT (SERPINB10)
HostRabbit
ReactivityHuman
Recommended DilutionELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000, IHC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
ClonalityPolyclonal
ConjugationUnconjugated
IsotypeIgG
PurificationPurified by antigen affinity column chromatography.
Size 1100 µg
Size 21 mg
FormLyophilized
Tested ApplicationsELISA, WB, IHC
BufferPrior to lyophilization: 1% BSA and 0.02% NaN3.
AvailabilityShipped within 7-15 working days.
StorageStore at -20 °C. Avoid repeated freeze/thaw cycles.
Dry IceNo
NCBI AccessionBC096217
AliasPI10,PI-10,Serpin B10,Bomapin,Peptidase inhibitor 10
BackgroundAntibody anti-SERPINB10
StatusRUO
NoteConcentration: Lyophilized form: Not applicable. After reconstitution: 1 mg/ml. -

Descripción

SERPINB10, a member of the serpin superfamily of serine protease inhibitors, plays a vital role in regulating proteolytic processes. Proteolytic enzymes are essential for many cellular functions, such as apoptosis, tissue remodeling, inflammation, and immunity. Dysregulation of these processes often leads to pathological conditions like cancer, fibrosis, and inflammatory diseases. Although most serpins inhibit serine proteases, SERPINB10's role extends to modulating intracellular proteolysis in non-canonical functions as well. Understanding SERPINB10 is crucial for deciphering how its aberrant expression impacts various diseases, including leukemia and other forms of cancer.

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