Heterochromatin-Associated Protein MENT (SERPINB10) Antibody
357.5€ (100 µg)
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Name
Heterochromatin-Associated Protein MENT (SERPINB10) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx122213
Tested Applications
ELISA, WB, IHC
Description
Rabbit Polyclonal against the SERPINB10 protein.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Heterochromatin-Associated Protein MENT (SERPINB10) Immunogen: Recombinant fragment corresponding to 209-396 AA of human SERPINB10. |
| Host | Rabbit |
| Reactivity | Human |
| Assay Type | Concentration: Lyophilized form: Not applicable. After reconstitution: 1 mg/ml. |
| Recommended Dilution | ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000, IHC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Observed MW: 45 kDa |
| Purification | Purified by antigen affinity column chromatography. |
| Size 1 | 100 µg |
| Size 2 | 1 mg |
| Form | Lyophilized |
| Tested Applications | ELISA, WB, IHC |
| Buffer | Prior to lyophilization: 1% BSA and 0.02% NaN3. |
| Availability | Shipped within 7-15 working days. |
| Storage | Store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| NCBI Accession | BC096217 |
| Alias | PI10,PI-10,Serpin B10,Bomapin,Peptidase inhibitor 10 |
| Background | Antibody anti-SERPINB10 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
SERPINB10, a member of the serpin superfamily of serine protease inhibitors, plays a vital role in regulating proteolytic processes. Proteolytic enzymes are essential for many cellular functions, such as apoptosis, tissue remodeling, inflammation, and immunity. Dysregulation of these processes often leads to pathological conditions like cancer, fibrosis, and inflammatory diseases. Although most serpins inhibit serine proteases, SERPINB10's role extends to modulating intracellular proteolysis in non-canonical functions as well. Understanding SERPINB10 is crucial for deciphering how its aberrant expression impacts various diseases, including leukemia and other forms of cancer.
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