SERPINB10 antibody
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935106861
info@markelab.com
name
SERPINB10 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab07743
tested applications
ELISA, WB, IF, IHC
Description
Protease inhibitor that may play a role in the regulation of protease activities during hematopoiesis and apoptosis induced by TNF. May regulate protease activities in the cytoplasm and in the nucleus.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | serpin peptidase inhibitor, clade B(ovalbumin), member 10 (SERPINB10) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 45 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IF, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P48595 |
| Gene ID | 5273 |
| Alias | PI10,PI-10,Serpin B10,Bomapin,Peptidase inhibitor 10 |
| Background | Antibody anti-SERPINB10 |
| Status | RUO |
| Note | Mol. Weight 45 kDa |
Descripción
SERPINB10, a member of the serpin superfamily of serine protease inhibitors, plays a vital role in regulating proteolytic processes. Proteolytic enzymes are essential for many cellular functions, such as apoptosis, tissue remodeling, inflammation, and immunity. Dysregulation of these processes often leads to pathological conditions like cancer, fibrosis, and inflammatory diseases. Although most serpins inhibit serine proteases, SERPINB10's role extends to modulating intracellular proteolysis in non-canonical functions as well. Understanding SERPINB10 is crucial for deciphering how its aberrant expression impacts various diseases, including leukemia and other forms of cancer.
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