anti- SERPINB10 antibody

Este producto es parte de SERPINB10 - serpin family B member 10
anti- SERPINB10 antibody

Pida mas información

935106861

info@markelab.com

Precio

Precio a consultar

Antibody anti-SERPINB10

proveedor

FineTest

reference

FNab07743

Tested Applications

ELISA, WB, IF, IHC

reactivity

human,mouse,rat

status

RUO

clonality

polyclonal

Descripción

Protease inhibitor that may play a role in the regulation of protease activities during hematopoiesis and apoptosis induced by TNF. May regulate protease activities in the cytoplasm and in the nucleus.


Background

SERPINB10, a member of the serpin superfamily of serine protease inhibitors, plays a vital role in regulating proteolytic processes. Proteolytic enzymes are essential for many cellular functions, such as apoptosis, tissue remodeling, inflammation, and immunity. Dysregulation of these processes often leads to pathological conditions like cancer, fibrosis, and inflammatory diseases. Although most serpins inhibit serine proteases, SERPINB10's role extends to modulating intracellular proteolysis in non-canonical functions as well. Understanding SERPINB10 is crucial for deciphering how its aberrant expression impacts various diseases, including leukemia and other forms of cancer.

Características del producto

category

Primary Antibodies


clonality

polyclonal


reactivity

human,mouse,rat


immunogen target

serpin peptidase inhibitor, clade B(ovalbumin), member 10


host

Rabbit


isotype

IgG


conjugation

Unconjugated


form

liquid


tested applications

ELISA, WB, IF, IHC


observerd MW

45 kDa


purity

≥95% as determined by SDS-PAGE


purification

Immunogen affinity purified


recommended dilution

WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200


size 1

100µg


storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)


or code

SERPINB10


alias

PI10,PI-10,Serpin B10,Bomapin,Peptidase inhibitor 10


note

This product is for research use only.


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