anti- SERPINB10 antibody
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935106861
info@markelab.com
Precio
Precio a consultar
Antibody anti-SERPINB10
proveedor
FineTestreference
FNab07743Tested Applications
ELISA, WB, IF, IHCreactivity
human,mouse,ratstatus
RUOclonality
polyclonalDescripción
Protease inhibitor that may play a role in the regulation of protease activities during hematopoiesis and apoptosis induced by TNF. May regulate protease activities in the cytoplasm and in the nucleus.
Background
SERPINB10, a member of the serpin superfamily of serine protease inhibitors, plays a vital role in regulating proteolytic processes. Proteolytic enzymes are essential for many cellular functions, such as apoptosis, tissue remodeling, inflammation, and immunity. Dysregulation of these processes often leads to pathological conditions like cancer, fibrosis, and inflammatory diseases. Although most serpins inhibit serine proteases, SERPINB10's role extends to modulating intracellular proteolysis in non-canonical functions as well. Understanding SERPINB10 is crucial for deciphering how its aberrant expression impacts various diseases, including leukemia and other forms of cancer.
Características del producto
category
Primary Antibodies
clonality
polyclonal
reactivity
human,mouse,rat
immunogen target
serpin peptidase inhibitor, clade B(ovalbumin), member 10
host
Rabbit
isotype
IgG
conjugation
Unconjugated
form
liquid
tested applications
ELISA, WB, IF, IHC
observerd MW
45 kDa
purity
≥95% as determined by SDS-PAGE
purification
Immunogen affinity purified
recommended dilution
WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200
size 1
100µg
storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
or code
SERPINB10
alias
PI10,PI-10,Serpin B10,Bomapin,Peptidase inhibitor 10
uniprot id
note
This product is for research use only.
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