Human Hereditary Hemochromatosis Protein (HFE) Protein
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Description
Human Hereditary Hemochromatosis Protein (HFE) is a recombinant protein expressed in E. coli. It consists of a single, non-glycosylated polypeptide chain containing 308 amino acids and is fused to an N-terminal His tag.
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Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Hereditary Hemochromatosis Protein (HFE) |
| Host | E. coli |
| Assay Type | Activity: Not tested Sequence Fragment: 23-306 AA. Tag: N-terminal His tag |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | 35.7 kDa |
| Expression | Recombinant |
| Purity | > 85% (SDS-PAGE) |
| Purification | Purified by proprietary chromatography techniques. <br> Sterile filtered. |
| Size 1 | 5 µg |
| Size 2 | 20 µg |
| Size 3 | 1 mg |
| Form | Liquid |
| Tested Applications | SDS-PAGE |
| Buffer | 20 mM Tris-HCl, pH 8.0, containing 0.4 M urea and 10% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Store at 4°C if entire vial will be used within 4 weeks. Aliquot and store at -20 °C for longer periods of time. For long term storage, it is recommended to add a carrier protein such as 0.1% HSA or BSA. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q30201 |
| Gene ID | 3077 |
| Background | Protein HFE |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. Concentration: 1 mg/ml |
Descripción
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HFE antibody
Binds to transferrin receptor(TFR) and reduces its affinity for iron-loaded transferrin.
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Hereditary Hemochromatosis Protein (HFE) Antibody
HFE Antibody is a Rabbit Polyclonal antibody against HFE. The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least nine alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined. [provided by RefSeq, Jul 2008].
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Hereditary Hemochromatosis Protein (HFE) Antibody
The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M).It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin.The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene.At least nine alternatively spliced variants have been described for this gene.Additional variants have been found but their full-length nature has not been determined.
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