HFE antibody
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Description
Binds to transferrin receptor(TFR) and reduces its affinity for iron-loaded transferrin.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | hemochromatosis (HFE) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1:500-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 45-58kd |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q30201 |
| Gene ID | 3077 |
| Alias | Hereditary hemochromatosis protein,HLA-H,HFE,HLAH |
| Background | Antibody anti-HFE |
| Status | RUO |
| Note | Mol. Weight 45-58 kDa |
Descripción
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HFE antibody
Binds to transferrin receptor(TFR) and reduces its affinity for iron-loaded transferrin.
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Hereditary Hemochromatosis Protein (HFE) Antibody
HFE Antibody is a Rabbit Polyclonal antibody against HFE. The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least nine alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined. [provided by RefSeq, Jul 2008].
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Hereditary Hemochromatosis Protein (HFE) Antibody
The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M).It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin.The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene.At least nine alternatively spliced variants have been described for this gene.Additional variants have been found but their full-length nature has not been determined.
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