Heme Oxygenase 2 (HMOX2) Antibody
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Description
Heme Oxygenase 2 Antibody is a Rabbit Polyclonal antibody against Heme Oxygenase 2. Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 isozymes, an inducible heme oxygenase-1 and a constitutive heme oxygenase-2. HMOX1 and Heme Oxygenase 2 belong to the heme oxygenase family. Alternative splice variants encoding the same protein have been identified at this locus.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Heme Oxygenase 2 (HMOX2) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | ELISA: 1 µg/ml, WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 20 µl |
| Size 2 | 100 µl |
| Size 3 | 2 × 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P30519 |
| Gene ID | 3163 |
| NCBI Accession | NP_002125.3 |
| Background | Antibody anti-HMOX2 |
| Status | RUO |
| Note | Concentration: 0.333 mg/ml - |
Descripción
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Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Heme oxygenase 2 could be implicated in the production of carbon monoxide in brain where it could act as a neurotransmitter.
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Heme Oxygenase 2 (HMOX2) Antibody
Heme Oxygenase 2 Antibody is a Rabbit Polyclonal antibody against Heme Oxygenase 2. Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 isozymes, an inducible heme oxygenase-1 and a constitutive heme oxygenase-2. HMOX1 and Heme Oxygenase 2 belong to the heme oxygenase family. Alternative splice variants encoding the same protein have been identified at this locus.
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