HDAC8 (pS39) Antibody

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Description
HDAC8 (pS39) Antibody is a Rabbit Polyclonal antibody against HDAC8 (pS39). Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene.
Documents del producto
Product specifications
| Category | Primary Antibodies  | 
| Immunogen Target | HDAC8 (pS39)  | 
| Host | Rabbit  | 
| Reactivity | Human  | 
| Recommended Dilution | IF/ICC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user.  | 
| Clonality | Polyclonal  | 
| Conjugation | Unconjugated  | 
| Isotype | IgG  | 
| Purification | Purified by affinity chromatography.  | 
| Size 1 | 20 µl  | 
| Size 2 | 100 µl  | 
| Size 3 | 2 × 100 µl  | 
| Form | Liquid  | 
| Tested Applications | IF/ICC  | 
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.  | 
| Availability | Shipped within 5-10 working days.  | 
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.  | 
| Dry Ice | No  | 
| UniProt ID | Q9BY41  | 
| Gene ID | 55869  | 
| Background | Antibody anti-HDAC8  | 
| Status | RUO  | 
| Note | Concentration: > 0.2 mg/ml -  | 
Descripción
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Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene.
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Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene.
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