Guinea pig Endothelin 1 (EDN1) ELISA Kit

Este producto es parte de EDN1-Endothelin 1
Guinea pig Endothelin 1 (EDN1) ELISA Kit
715€ (96 tests)

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Name
Guinea pig Endothelin 1 (EDN1) ELISA Kit
Category
ELISA Kits
Provider
Abbexa
Reference
abx150412
Tested Applications
ELISA

Description

Guinea pig Endothelin 1 (EDN1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Guinea pig Endothelin 1 (EDN1) concentrations in serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Endothelin 1 (EDN1)

Documentos del producto

Instrucciones
Descargar
Data sheet
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Especificaciones del producto

Category
ELISA Kits
Immunogen Target
Endothelin 1 (EDN1)
Reactivity
Guinea pig
Detection Method
Colorimetric
Assay Data
Quantitative
Assay Type
Competitive
Test Range
6.17 pg/ml - 500 pg/ml
Sensitivity
< 2.51 pg/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Size 2
5 × 96 tests
Size 3
10 × 96 tests
Form
Standard Form: Lyophilized
Tested Applications
ELISA
Sample Type
Serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.
Availability
Shipped within 5-7 working days.
Storage
Shipped at 4°C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
Alias
ARCND3,ET1, ET-1,HDLCQ7,QME,PPET1
Background
Elisa Kits for: EDN1
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout.

Background

Endothelin-1 (EDN1) is a peptide hormone belonging to the endothelin family. It plays a crucial role in regulating blood vessel contraction and dilation, thereby influencing blood pressure and blood flow throughout the body. Endothelin-1 is primarily produced by endothelial cells, It is also produced by other cell types, including vascular smooth muscle cells, cardiomyocytes, and certain inflammatory cells.Endothelin-1 acts as a potent vasoconstrictor, meaning it causes blood vessels to narrow, leading to an increase in blood pressure. Dysregulation of endothelin-1 signaling is associated with several cardiovascular disorders, including hypertension, atherosclerosis, coronary artery disease, and pulmonary hypertension. Elevated levels of endothelin-1 have been observed in individuals with these conditions, contributing to their pathogenesis. Endothelin-1 is able to bind to specific receptors on target cells known as endothelin receptors. There are two main types of endothelin receptors: endothelin receptor type A (ETA) and endothelin receptor type B (ETB).

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