GSK3 alpha (Phospho-Ser21) Antibody

Product Graph
52€ (10 µg)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
GSK3 alpha (Phospho-Ser21) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx012539
tested applications
ELISA, WB, IHC, IP

Description

Rabbit polyclonal antibody against GSK3 alpha protein. Immunogen region is N-terminal. Specificity is as follows for the reactive species: H:S21, M:S21, R:S21.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
GSK3 alpha
Host
Rabbit
Reactivity
Human, Mouse, Rat
Recommended Dilution
WB: 1/500 - 1/3000, IHC: 1/50 - 1/100, ELISA: 1/20000. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen.
Size 1
10 µg
Size 2
100 µg
Size 3
200 µg
Size 4
300 µg
Size 5
1 mg
Form
Liquid
Tested Applications
ELISA, WB, IHC, IP
Buffer
PBS (without Mg<sup>2+</sup> and Ca<sup>2+</sup>), pH 7.4, 150 mM NaCl, 0.02% sodium azide, 50% glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P49840
Background
Antibody anti-GSK3
Status
RUO
Note
Concentration: 1 mg/ml -

Descripción

Related Products

abx000124

Glycogen Synthase Kinase 3 Beta Phospho-Ser9 (GSK3B pS9) Antibody

Glycogen Synthase Kinase 3 Beta Phospho-Ser9 (GSK3B pS9) Antibody is a Rabbit Polyclonal antibody against Glycogen Synthase Kinase 3 Beta Phospho-Ser9 (GSK3B pS9). The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Ver Producto
abx010857

GSK3 alpha Antibody

Glycogen synthase kinase 3 alpha belongs to the Ser/Thr family of protein kinases, Cdc2/cdkx subfamily, GSK3 subsubfamily. It is implicated in the hormonal control of several regulatory proteins including glycogen synthase, myb, and the transcription factor c jun. GSK3 phosphorylates glycogen synthase and thereby inactivates it. Insulin stimulates the dephosphorylation of glycogen synthase at the sites phosphorylated by GSK3 and subsequently inhibits GSK3 acutely leading to the stimulation of glycogen synthesis. GSK3 signaling is performed by two isoforms, GSK3 alpha and GSK3 beta. The two isoforms share 97% sequence similarity within their catalytic domains. GSK3 has also been shown to play a role in protein synthesis, cell adhesion, cell proliferation, cell differentiation, microtubule dynamics and cell motility.

Ver Producto
abx012539

GSK3 alpha (Phospho-Ser21) Antibody

Rabbit polyclonal antibody against GSK3 alpha protein. Immunogen region is N-terminal. Specificity is as follows for the reactive species: H:S21, M:S21, R:S21.

Ver Producto