Growth Hormone Variant (GH2) Antibody
364€ (100 µg)
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935106861
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name
Growth Hormone Variant (GH2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx233448
tested applications
ELISA, WB, IHC
Description
GH2 Antibody is a Rabbit Polyclonal against GH2.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Growth Hormone Variant (GH2) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1/500 - 1/2000, IHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P01242 |
| Alias | GHL,GHV,GH-V,GHB2,hGH-V,Growth hormone variant,Placenta-specific growth hormone |
| Background | Antibody anti-GH2 |
| Status | RUO |
| Note | Concentration: 2 mg/ml - Validity: 12 months. |
Descripción
Growth hormone 2 (GH2) is a member of the growth hormone gene family primarily expressed in the placenta, where it plays a critical role in regulating fetal growth and maternal metabolic adaptations during pregnancy GH2 is structurally similar to growth hormone 1 (GH1) but has distinct roles in enhancing placental development and nutrient transport to the fetus It stimulates insulin-like growth factor 1 (IGF-1) production and modulates maternal glucose and lipid metabolism to ensure fetal nutrient supply Dysregulation of GH2 expression has been associated with placental insufficiency, intrauterine growth restriction (IUGR), and gestational diabetes GH2 also influences immune responses during pregnancy, promoting tolerance to the fetus while maintaining maternal immunity Emerging studies suggest that alterations in GH2 expression may contribute to pregnancy complications and metabolic disorders, highlighting its importance in fetal development and maternal physiology
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