Growth Differentiation Factor 15 (GDF15) Antibody Pair

Este producto es parte de GDF15 - Growth Differentiation Factor 15
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1521€ (5 × 96 tests)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
Growth Differentiation Factor 15 (GDF15) Antibody Pair
category
Antibody Pairs
provider
Abbexa
reference
abx370308
tested applications
ELISA

Description

Growth Differentiation Factor 15 (GDF15) Antibody Pair for use in Sandwich ELISA assay development. 

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Antibody Pairs
Immunogen Target
Growth Differentiation Factor 15 (GDF15)
Reactivity
Human
Assay Data
Detection Antibody Biotinilated
Assay Type
Sandwich
Recommended Dilution
Dilute the Capture Antibody 125-fold with Coating Buffer.  Dilute the Biotin-Conjugated Detection Antibody 200-fold with Detection Antibody Diluent.  Optimal dilutions/concentrations should be determined by the end user.
Size 1
5 × 96 tests
Size 2
10 × 96 tests
Form
Standard: Lyophilized--Liquid (Capture Antibody and Detection Antibody)
Reconstitute the standard with Standard Diluent. The volume, and therefore standard concentration, should be determined by the end user.
Tested Applications
ELISA
Buffer
The Capture and Detection Antibody both contain 0.1% sodium azide.
Availability
Please enquire.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
Alias
HG,PDF,MIC1;,PLAB,MIC-1,NAG-1,PTGFB, GDF-15
Background
Antibody Pair for GDF15
Status
RUO
Note
This antibody pair contains ( 5 x 96 det):    Detection:  50 µg  Capture:  200 µg  Standard:  2 µg
This product is for research use only.

Descripción

GDF15, a stress-responsive cytokine, stands as a distinct member within the diverse TGF-β superfamily. Its expression is typically low in most tissues during normal physiological conditions. However, when cardiac myocytes face ischemia or heightened ventricular wall stress, GDF-15 expression intensifies significantly. This cytokine has emerged as a potent prognostic indicator in various diseases, including heart diseases and cancer. Interestingly, it appears to act protectively against cardiac injury, attributed to its antihypertrophic, antiapoptotic, and anti-inflammatory properties, although the specific receptor through which GDF-15 exerts its effects remains unidentified. Studies have revealed a positive correlation between elevated GDF-15 levels and factors such as LV mass, IL-6, and MMP-9 levels in patients with heart failure (HF)

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