Growth Arrest And DNA Damage-Inducible, Alpha (GADD45A) Antibody

312€ (60 µl)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Growth Arrest And DNA Damage-Inducible, Alpha (GADD45A) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx001489
tested applications
WB, IHC
Description
GADD45A Antibody is a Rabbit Polyclonal antibody against GADD45A. This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Primary Antibodies |
Immunogen Target | Growth Arrest And DNA Damage-Inducible, Alpha (GADD45A) |
Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Recommended Dilution | WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Purification | Purified by affinity chromatography. |
Size 1 | 60 µl |
Size 2 | 120 µl |
Size 3 | 200 µl |
Form | Liquid |
Tested Applications | WB, IHC |
Buffer | PBS, pH 7.3, containing 0.01% thiomersal, 50% glycerol. |
Availability | Shipped within 5-10 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | P24522 |
Gene ID | 1647 |
NCBI Accession | NP_001915.1 |
Background | Antibody anti-GADD45A |
Status | RUO |
Note | Concentration: 1 mg/ml - |
Descripción
Related Products

Human GADD45A (Growth arrest and DNA damage-inducible protein GADD45 alpha) ELISA Kit
Ver Producto
GADD45A antibody
In T-cells, functions as a regulator of p38 MAPKs by inhibiting p88 phosphorylation and activity(By similarity). Might affect PCNA interaction with some CDK(cell division protein kinase) complexes; stimulates DNA excision repair in vitro and inhibits entry of cells into S phase.
Ver Producto