GP145-TrkB/GP95-TrkB (TrkB) Antibody

Este producto es parte de NTRK - neurotrophic receptor tyrosine kinase
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357.5€ (100 µg)

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935106861
info@markelab.com
name
GP145-TrkB/GP95-TrkB (TrkB) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx038380
tested applications
ELISA, IF/ICC

Description

Rabbit Polyclonal against the TrkB protein.

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryPrimary Antibodies
Immunogen TargetGP145-TrkB/GP95-TrkB (TrkB)
HostRabbit
ReactivityHuman
Recommended DilutionELISA: 1/20000 - 1/80000, IF/ICC: 1/100 - 1/500. Optimal dilutions/concentrations should be determined by the end user.
ClonalityPolyclonal
ConjugationUnconjugated
IsotypeIgG
PurificationPurified by Protein A/G column chromatography.
Size 1100 µg
Size 21 mg
FormLyophilized
Tested ApplicationsELISA, IF/ICC
BufferPrior to lyophilization: 0.02% NaN3.
AvailabilityShipped within 7-15 working days.
StorageStore at -20 °C. Avoid repeated freeze/thaw cycles.
Dry IceNo
NCBI AccessionNM_001007097
AliasOBHD,TRKB,DEE58,trk-B,EIEE58,GP145-TrkB,Tropomyosin-related kinase B,TrkB tyrosine kinase,Neurotrophic tyrosine kinase receptor type 2,BDNF/NT-3 growth factors receptor
BackgroundAntibody anti-NTRK2
StatusRUO
NoteConcentration: Lyophilized form: Not applicable. After reconstitution: 1 mg/ml. -

Descripción

Neurotrophic receptor tyrosine kinase 2 (NTRK2), often referred to as TrkB, interacts specifically with brain-derived neurotrophic factor (BDNF) and neurotrophin-4/5 (NT-4/5). This receptor is central to processes like neuroplasticity, synaptic strength regulation, and long-term potentiation—mechanisms foundational for cognitive functions such as learning and memory. In addition to its role in brain health, NTRK2 is involved in mood regulation, and aberrations in its signaling pathways are associated with neuropsychiatric disorders, including depression, anxiety, and schizophrenia, emphasizing its role in mental health research and therapeutic interventions.
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