GP145-TrkB/GP95-TrkB (TrkB) Antibody
357.5€ (100 µg)
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935106861
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name
GP145-TrkB/GP95-TrkB (TrkB) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx038380
tested applications
ELISA, IF/ICC
Description
Rabbit Polyclonal against the TrkB protein.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | GP145-TrkB/GP95-TrkB (TrkB) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1/20000 - 1/80000, IF/ICC: 1/100 - 1/500. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by Protein A/G column chromatography. |
| Size 1 | 100 µg |
| Size 2 | 1 mg |
| Form | Lyophilized |
| Tested Applications | ELISA, IF/ICC |
| Buffer | Prior to lyophilization: 0.02% NaN3. |
| Availability | Shipped within 7-15 working days. |
| Storage | Store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| NCBI Accession | NM_001007097 |
| Alias | OBHD,TRKB,DEE58,trk-B,EIEE58,GP145-TrkB,Tropomyosin-related kinase B,TrkB tyrosine kinase,Neurotrophic tyrosine kinase receptor type 2,BDNF/NT-3 growth factors receptor |
| Background | Antibody anti-NTRK2 |
| Status | RUO |
| Note | Concentration: Lyophilized form: Not applicable. After reconstitution: 1 mg/ml. - |
Descripción
Neurotrophic receptor tyrosine kinase 2 (NTRK2), often referred to as TrkB, interacts specifically with brain-derived neurotrophic factor (BDNF) and neurotrophin-4/5 (NT-4/5). This receptor is central to processes like neuroplasticity, synaptic strength regulation, and long-term potentiation—mechanisms foundational for cognitive functions such as learning and memory. In addition to its role in brain health, NTRK2 is involved in mood regulation, and aberrations in its signaling pathways are associated with neuropsychiatric disorders, including depression, anxiety, and schizophrenia, emphasizing its role in mental health research and therapeutic interventions.
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