Goat Interleukin 15 (IL15) Protein

Product specifications

Proteins and Peptides

Interleukin 15 (IL15)

E. coli

Goat

Unconjugated

Concentration: Prior to lyophilization: 200 µg/ml
Sequence Fragment: Please enquire.
Tag: N-terminal His tag

Recombinant

> 90%

1 mg

5 mg

Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.

WB, SDS-PAGE

Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.

Shipped within 1-2 months.

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.

No

IL-15

Protein IL15

RUO

This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

Interleukin 15 (IL15) is a pro-inflammatory cytokine that plays a crucial role in regulating innate and adaptive immune responses, particularly by supporting the development, activation, and survival of natural killer (NK) cells and CD8+ T cells. IL-15 is essential for immune surveillance and protection against viral infections and tumors, making it an important cytokine in both immunity and immunotherapy. IL-15 was first identified as a T-cell growth factor similar to IL-2, but it is now recognized as a distinct cytokine with a unique biological role. It is expressed by a wide range of cell types, including monocytes, macrophages, dendritic cells, epithelial cells, and fibroblasts, in response to various inflammatory stimuli. Unlike many cytokines that are secreted and act in an autocrine or paracrine fashion, IL-15 primarily functions through a unique mechanism called trans-presentation, where it binds to its receptor on neighboring cells via cell-cell contact, thus delivering potent activation signals.

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