Glycoprotein 5 (GP5) Antibody
286€ (50 tests)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Glycoprotein 5 (GP5) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx270274
tested applications
FCM
Description
Glycoprotein V, Platelet (GP5) Antibody is a Rabbit Polyclonal Antibody against Glycoprotein V, Platelet (GP5) for use in flow cytometry.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Glycoprotein 5 (GP5) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | FCM: 1-5 µl/106 cells. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by antigen-specific affinity chromatography. |
| Size 1 | 50 tests |
| Size 2 | 100 tests |
| Size 3 | 200 tests |
| Size 4 | 500 tests |
| Form | Liquid |
| Tested Applications | FCM |
| Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Shipped within 5-15 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | GPV,CD42d,Platelet glycoprotein V,GPV,Glycoprotein 5,CD42d |
| Background | Antibody anti-GP5 |
| Status | RUO |
Descripción
Glycoprotein V (GP5) is a key platelet membrane protein that functions as a part of the GPIb-IX-V complex, a receptor system primarily responsible for mediating platelet adhesion during vascular injury. This complex is crucial for the initial steps of platelet plug formation, which is essential in the process of hemostasis, particularly in the high-shear conditions of arterial blood flow. GP5 serves as an accessory component in the complex, complementing the roles of other glycoproteins like GPIbα (GP1BA), GPIbβ (GP1BB), and GPIX (GP9). The GPIb-IX-V complex, including GP5, binds to von Willebrand factor (vWF), which facilitates platelet tethering to the damaged endothelium under conditions of high shear stress. Although GP5 is not the primary binding site for vWF (that role belongs to GP1BA), it contributes to the structural integrity and function of the receptor. GP5 may also interact with other ligands and is thought to regulate the binding activity of the GPIb-IX-V complex.
Related Products
Human GP5 (Platelet glycoprotein V) ELISA Kit
Ver Producto
Mouse Glycoprotein 5 (GP5) Protein
Recombinant Glycoprotein V, Platelet (GP5) is a recombinant Mouse protein produced in a Prokaryotic expression system (E. coli).
Ver Producto