Glutathione Peroxidase 1 (GPX1) Antibody

Glutathione Peroxidase 1 (GPX1) Antibody
312€ (60 µl)

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Name
Glutathione Peroxidase 1 (GPX1) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx001027
Tested Applications
WB, IF/ICC

Description

GPX1 Antibody is a Rabbit Polyclonal antibody against GPX1. This gene encodes a member of the glutathione peroxidase family. Glutathione peroxidase functions in the detoxification of hydrogen peroxide, and is one of the most important antioxidant enzymes in humans. This protein is one of only a few proteins known in higher vertebrates to contain selenocysteine, which occurs at the active site of glutathione peroxidase and is coded by UGA, that normally functions as a translation termination codon. In addition, this protein is characterized in a polyalanine sequence polymorphism in the N-terminal region, which includes three alleles with five, six or seven alanine (ALA) repeats in this sequence. The allele with five ALA repeats is significantly associated with breast cancer risk. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Documentos del producto

Instrucciones
Data sheet
Descargar

Especificaciones del producto

Category
Primary Antibodies
Immunogen Target
Target: Glutathione Peroxidase 1 (GPX1)
Immunogen: A synthetic peptide corresponding to human GPX1
Host
Rabbit
Reactivity
Human, Mouse, Rat
Assay Type
Concentration: 1 mg/ml
Recommended Dilution
WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
Calculated MW: 10 kDa/22 kDa  Observed MW: 22 kDa
Purification
Purified by affinity chromatography.
Size 1
60 µl
Size 2
120 µl
Size 3
200 µl
Form
Liquid
Tested Applications
WB, IF/ICC
Buffer
PBS, pH 7.3, containing 0.01% thiomersal, 50% glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P07203
Gene ID
2876
NCBI Accession
NP_000572.2
Background
Antibody anti-GPX1
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

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