Glutathione Hydrolase 4 (gGT4) Antibody

Este producto es parte de GGT - Gamma-Glutamyltransferase
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52€ (10 µg)

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935106861
info@markelab.com
name
Glutathione Hydrolase 4 (gGT4) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx015589
tested applications
ELISA, WB

Description

Rabbit polyclonal antibody against Gamma-glutamyltransferase 4 protein. Immunogen region is Internal. Specificity is as follows for the reactive species: H:T472, M:T472, R:T472.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Glutathione Hydrolase 4 (gGT4)
Host
Rabbit
Reactivity
Human, Mouse, Rat
Recommended Dilution
WB: 1/500 - 1/3000, ELISA: 1/10000. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen.
Size 1
10 µg
Size 2
100 µg
Size 3
200 µg
Size 4
300 µg
Size 5
1 mg
Form
Liquid
Tested Applications
ELISA, WB
Buffer
PBS (without Mg<sup>2+</sup> and Ca<sup>2+</sup>), pH 7.4, 150 mM NaCl, 0.02% sodium azide, 50% glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q9UJ14
Alias
GGT4,GGTL3,GGTL5,D20S101,Gamma-glutamyltransferase like 5,Gamma-glutamyltransferase like 5,Glutathione hydrolase 7
Background
Antibody anti-GGT7
Status
RUO
Note
Concentration: 1 mg/ml - 

Descripción

Gamma-glutamyltransferase 7 (GGT7) is another member of the gamma-glutamyltransferase enzyme family involved in the breakdown and recycling of glutathione, a critical molecule for antioxidant defense and detoxification pathways GGT7 is expressed in tissues such as the kidney, liver, and lungs, where it regulates the metabolism of gamma-glutamyl compounds, supporting amino acid transport and redox homeostasis Dysregulation of GGT7 activity has been associated with metabolic disorders, cardiovascular diseases, and cancers, where it contributes to oxidative stress and inflammation GGT7 is particularly relevant in tumor biology, where its role in glutathione metabolism supports cellular survival under oxidative stress conditions Elevated GGT7 expression has been linked to drug resistance in cancer cells by enhancing detoxification pathways Its emerging role in immune regulation and cellular stress responses highlights its importance in maintaining homeostasis under physiological and pathological conditions

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Glutathione Hydrolase 4 (gGT4) Antibody

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Ver Producto