Glial Cell Line Derived Neurotrophic Factor (GDNF) Antibody

Glial Cell Line Derived Neurotrophic Factor (GDNF) Antibody
292.5€ (80 µl)

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Name
Glial Cell Line Derived Neurotrophic Factor (GDNF) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx034059
Tested Applications
ELISA, IHC, FCM

Description

GDNF is a highly conserved neurotrophic factor. The recombinant form of this protein was shown to promote the survival and differentiation of dopaminergic neurons in culture, and was able to prevent apoptosis of motor neurons induced by axotomy. This protein is processed to a mature secreted form that exists as a homodimer. The mature form of the protein is a ligand for the product of the RET (rearranged during transfection) protooncogene. In addition to the transcript encoding GDNF, two additional alternative transcripts encoding distinct proteins, referred to as astrocyte-derived trophic factors, have also been described.

Documentos del producto

Instrucciones
Data sheet
Descargar

Especificaciones del producto

Category
Primary Antibodies
Immunogen Target
Target: Glial Cell Line Derived Neurotrophic Factor (GDNF)
Immunogen: KLH-conjugated synthetic peptide between 8-36 amino acids from the N-terminal region of human GDNF.
Host
Rabbit
Reactivity
Human
Recommended Dilution
IHC-P: 1/10 - 1/50, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
Calculated MW: 23.7 kDa
Purification
Purified through a protein A column, followed by peptide affinity purification.
Size 1
80 µl
Size 2
400 µl
Form
Liquid
Tested Applications
ELISA, IHC, FCM
Buffer
PBS containing 0.09% sodium azide.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P39905
Background
Antibody anti-GDNF
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

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