GIPC PDZ Domain Containing Family, Member 2 (GIPC2) Antibody
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Description
GIPC2 Antibody is a Rabbit Polyclonal antibody against GIPC2. The eukaryotic PDZ domain is a multifunctional protein-protein interacting motif that is found in a variety of proteins and is involved in both the clustering of signaling molecules and the organization of protein networks. GIPC2 (GIPC PDZ domain containing family, member 2), also known as SEMCAP2, is a 315 amino acid protein that localizes to the cytoplasm and contains one PDZ domain. Expressed at high levels in kidney and colon and at lower levels in adult liver, GIPC2 interacts with SEMA5A and is thought to function as a scaffold protein, possibly modulating cell adhesion and growth factor signaling and playing a role in tumorigenesis. The gene encoding GIPC2 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: GIPC PDZ Domain Containing Family, Member 2 (GIPC2) Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-315 of human GIPC2. |
| Host | Rabbit |
| Reactivity | Human |
| Assay Type | Concentration: > 0.2 mg/ml |
| Recommended Dilution | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Calculated MW: 34 kDa Observed MW: 34 kDa |
| Purification | Purified by affinity chromatography. |
| Size 1 | 20 µl |
| Size 2 | 100 µl |
| Size 3 | 2 × 100 µl |
| Form | Liquid |
| Tested Applications | WB |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q8TF65 |
| Gene ID | 54810 |
| NCBI Accession | NP_060125.4 |
| Background | Antibody anti-GIPC2 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
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GIPC PDZ Domain Containing Family, Member 2 (GIPC2) Antibody
GIPC2 Antibody is a Rabbit Polyclonal antibody against GIPC2. The eukaryotic PDZ domain is a multifunctional protein-protein interacting motif that is found in a variety of proteins and is involved in both the clustering of signaling molecules and the organization of protein networks. GIPC2 (GIPC PDZ domain containing family, member 2), also known as SEMCAP2, is a 315 amino acid protein that localizes to the cytoplasm and contains one PDZ domain. Expressed at high levels in kidney and colon and at lower levels in adult liver, GIPC2 interacts with SEMA5A and is thought to function as a scaffold protein, possibly modulating cell adhesion and growth factor signaling and playing a role in tumorigenesis. The gene encoding GIPC2 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome.
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