General Transcription Factor IIH, Polypeptide 3 (GTF2H3) Antibody
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Description
GTF2H3 Antibody is a Rabbit Polyclonal antibody against GTF2H3. This gene encodes a member of the TFB4 family. The encoded protein is a subunit of the core-TFIIH basal transcription factor and localizes to the nucleus. The encoded protein is involved in RNA transcription by RNA polymerase II and nucleotide excision repair and associates with the Cdk-activating kinase complex. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 14.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | General Transcription Factor IIH, Polypeptide 3 (GTF2H3) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | ELISA: 1 µg/ml, WB: 1/500 - 1/2000, IP: 0.5 µg - 4 µg antibody per 200 µg - 400 µg extracts of whole cells. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 20 µl |
| Size 2 | 100 µl |
| Size 3 | 2 × 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IP |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q13889 |
| Gene ID | 2967 |
| NCBI Accession | NP_001507.2 |
| Background | Antibody anti-GTF2H3 |
| Status | RUO |
| Note | Concentration: > 0.2 mg/ml - |
Descripción
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Component of the core-TFIIH basal transcription factor involved in nucleotide excision repair(NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. Anchors XPB.
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General Transcription Factor IIH, Polypeptide 3 (GTF2H3) Antibody
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