GATA Binding Protein 5 (GATA5) Antibody

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Description
The protein encoded by this gene is a transcription factor that contains two GATA-type zinc fingers. The encoded protein is known to bind to hepatocyte nuclear factor-1 alpha (HNF-1 alpha), and this interaction is essential for cooperative activation of the intestinal lactase-phlorizin hydrolase promoter. In other organisms, similar proteins may be involved in the establishment of cardiac smooth muscle cell diversity.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | GATA Binding Protein 5 (GATA5) |
| Host | Mouse |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1/10000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG1 |
| Purification | Unpurified ascites. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9BWX5 |
| Gene ID | 140628 |
| OMIM | 611496 |
| Background | Antibody anti-GATA5 |
| Status | RUO |
| Note | Concentration: Not determined. - |
Descripción
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GATA5 antibody
Transcription factor required during cardiovascular development(PubMed:23289003). Plays an important role in the transcriptional program(s) that underlies smooth muscle cell diversity(By similarity). Binds to the functionally important CEF-1 nuclear protein binding site in the cardiac-specific slow/cardiac troponin C transcriptional enhancer(PubMed:25543888).
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GATA Binding Protein 5 (GATA5) Antibody
The protein encoded by this gene is a transcription factor that contains two GATA-type zinc fingers. The encoded protein is known to bind to hepatocyte nuclear factor-1 alpha (HNF-1 alpha), and this interaction is essential for cooperative activation of the intestinal lactase-phlorizin hydrolase promoter. In other organisms, similar proteins may be involved in the establishment of cardiac smooth muscle cell diversity.
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