Gamma-Aminobutyric Acid Receptor Subunit Alpha-4 (gABRA4) Antibody

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312€ (60 µl)

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935106861
info@markelab.com
name
Gamma-Aminobutyric Acid Receptor Subunit Alpha-4 (gABRA4) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx002817
tested applications
WB

Description

gABRA4 Antibody is a Rabbit Polyclonal antibody against gABRA4. Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. This gene encodes subunit alpha-4, which is involved in the etiology of autism and eventually increases autism risk through interaction with another subunit, gamma-aminobutyric acid receptor beta-1 (GABRB1). Alternatively spliced transcript variants encoding different isoforms have been found in this gene.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
Gamma-Aminobutyric Acid Receptor Subunit Alpha-4 (gABRA4)
Host
Rabbit
Reactivity
Rat
Recommended Dilution
WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Purified by affinity chromatography.
Size 1
60 µl
Size 2
120 µl
Size 3
200 µl
Form
Liquid
Tested Applications
WB
Buffer
PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P48169
Gene ID
2557
NCBI Accession
NP_000800.2
Background
Antibody anti-gABRA4
Status
RUO
Note
Concentration: 1 mg/ml -

Descripción

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