G Protein-Coupled Receptor Kinase 6 (GRK6) Antibody
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
GRK6 Antibody is a Rabbit Polyclonal against GRK6.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | G Protein-Coupled Receptor Kinase 6 (GRK6) |
| Host | Rabbit |
| Reactivity | Human, Rat |
| Recommended Dilution | WB: 1/500 - 1/2000, IHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 20 µl |
| Size 2 | 50 µl |
| Size 3 | 100 µl |
| Size 4 | 200 µl |
| Size 5 | 1 ml |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P43250 |
| Gene ID | 2870 |
| NCBI Accession | NP_001004105.1, NM_001004105.2, NP_001004106.1, NM_001004106.2 |
| OMIM | 600869 |
| Background | Antibody anti-GRK6 |
| Status | RUO |
Descripción
Related Products
GRK6 antibody
Specifically phosphorylates the activated forms of G protein-coupled receptors. Such receptor phosphorylation initiates beta-arrestin-mediated receptor desensitization, internalization, and signaling events leading to their desensitization. Seems to be involved in the desensitization of D2-like dopamine receptors in striatum and chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis(By similarity). Phosphorylates rhodopsin(RHO)(in vitro) and a non G-protein-coupled receptor: LRP6 during Wnt signaling(in vitro).
Ver Producto
G Protein-Coupled Receptor Kinase 6 (GRK6) Antibody
GRK6 Antibody is a Rabbit Polyclonal antibody against GRK6. This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating their deactivation. Several transcript variants encoding different isoforms have been described for this gene.
Ver Producto
G Protein-Coupled Receptor Kinase 6 (GRK6) Antibody
Rabbit polyclonal antibody against GRK6 protein. Immunogen region is N-terminal.
Ver Producto